Clinical profile and outcomes of trauma patients visiting the emergency department of a trauma center Addis Ababa, Ethiopia

Abebe, Tesfaye; Boru, Yared; Belay, Ermiyas; Abebe, Asmamaw; Kefyalew, Merahi; Kifle, Fitsum

doi:10.1016/j.afjem.2022.10.013

Cited by 4 publications

(5 citation statements)

References 23 publications

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“…In this study, males are more than females, 86% were males and 14% were females. The findings are similar with the study in which 71% were males while 29% were females 14 . In other study by Kundavaram Paul, males were 74% and 36% were females 15 .…”

Section: Fig 3: Gcs Score Of Patients (N=305)supporting

confidence: 91%

“…In another study, the results were different than this study, about 31% patients had road traffic accident, out of which pedestrians were commonest (62.1%), minibus accidents (32.5%) then passengers (26.2%) and motorcyclist (8.1%) 14 . A study by Sema Puskulluoglu, about 9% patients had road traffic accidents 13 .…”

Section: Fig 3: Gcs Score Of Patients (N=305)contrasting

confidence: 79%

“…The findings were similar in study by Frederik Trier et al, like fall (20.3%) is commonest followed by pedestrian injury (5.5%), violence (5.2%), stabbing (2.9%) and gunshot (0.5%) 17 . Other study in Ethiopia showed that fall down was commonest (23.5%) followed by fighting, (31.8%), machine injury (9.4%), stab injury (3%) and burn (1.1%) 14 . A study by Sema Puskulluoglu, injuries were common due to simple extremities injuries (41%), falls (33%), stab wound (10.3%), burns (1.6%), electric shock (0,2%) 13 .…”

Section: Fig 3: Gcs Score Of Patients (N=305)mentioning

confidence: 91%

“…A study by Ozgur Sogut, males were 68% while females were 32% 12 . A study done in Ethiopia by Tesfaye Abebe, males were 71% females 29% were male 14 . In a study by Laurent G. Glance, males were 64% while 36% were females 16 .…”

Section: Fig 3: Gcs Score Of Patients (N=305)mentioning

confidence: 99%

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2024

IJPSR

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Introduction:The Emergency Medicine Department presents distinct challenges, both diagnostic uncertainty and time constraints. Promptly administering the right drugs in this setting can be crucial for saving lives. Hence, we conducted a study to analyse the prescriptions in the patients admitted to Emergency Medicine Department. Method: This is a prospective, observational single center study conducted at the Emergency Medicine department for one year. The study was started after approval from Institutional Review Board (IRB). All patients of any gender and any co-morbidities admitted to emergency medicine department were included in the study. Results: In this study, total 305 patients included, out of which majority 79 (25.9%) patients were in the age young group 31-40 years. Gender distribution depicts 262 (85.9%) and 43 (14.09%) were males and females respectively. Two wheeler accidents 119 (39.01%) were the most common. Total 186 (64.13%) patients having GCS score 11-15. Pantoprazole was the most commonly prescribed drug, prescribed in 200 (81.96%) prescriptions. Ondansetron was in used in 90 (28.19%) patients. Cefixime is used in 70 (22.95%), ofloxacin in 30 (9.83%). The fixed drug combination, Glipizide + Metformin was used in 36 (11.80%) patients. Conclusion: Our study provides various insights into the analysis of prescribing drugs in the uniquely challenging environment of the Emergency department. The prescribed medications in the study were as per the patient's condition. We propose that future studies should be conducted to explore the rational management of patients. INTRODUCTION:Prescribing medications poses constant difficulties for healthcare providers, particularly in emergency situations. The Emergency Department presents distinct challenges, as clinicians often encounter both diagnostic uncertainty and time constraints. Promptly administering the right drugs in this setting can be crucial for saving lives 1 .

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Section: Fig 3: Gcs Score Of Patients (N=305)supporting

confidence: 91%

Section: Fig 3: Gcs Score Of Patients (N=305)contrasting

confidence: 79%

Section: Fig 3: Gcs Score Of Patients (N=305)mentioning

confidence: 91%

Section: Fig 3: Gcs Score Of Patients (N=305)mentioning

confidence: 99%

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2024

IJPSR

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“…Порушення загоєння ушкоджень м'яких тканин є однією з найпоширеніших проблем сучасної медицини. Повношарові рани шкіри і розташованих під нею м'язів часто утворюються у населення всього світу внаслідок побутового травматизму, транспортних і виробничих аварій і складають 44-49 % у структурі політравми мирного часу [1,2]. В умовах військового часу кількість поранень м'яких тканин різко зростає, і складає в Україні 64-68% від загальної кількості бойових травм [2,3].…”

Section: гістологічна характеристикаunclassified

Histological Characteristics of Experimental Wounds of Soft Tissues of the Femur of Rats and the Role of IFN-γ in the Dynamics of their Healing

Іонов¹,

Komisova²

2022

Ukr. ž. med. bìol. sportu

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The purpose of the study was to evaluate the histomorphological changes in samples of the wound canal of the soft tissues of the femur of rats and to study the role of interferon-gamma (IFN-γ) in the dynamics of wound healing. Materials and methods. The study was conducted on 24 Wistar rats. Animals were divided into two groups – intact (6 rats) and experimental (18 rats). Animals of the experimental group were used to simulate wounds. Rats were euthanized on the 10th, 20th, and 40th days (6 animals for each time) after wound simulation. Blood for the study was taken by the method of open cardiac puncture. The levels of INF-γ in the blood serum of animals were determined by enzyme immunoassay. Histological processing of the samples was carried out according to generally accepted methods, the sections were stained with hematoxylin and eosin, as well as picrofuchsin according to Van Gieson. Results and discussion. The work revealed changes in the expression of IFN-γ in the blood serum of animals with wounds: an increase in the levels of IFN-γ on the 10th and 20th days after modeling wounds compared to the levels of rats in the intact group (p<0.05). A decrease in the levels of IFN-γ on the 40th day of the experiment compared to a similar level of this cytokine on the 10th and 20th days after wound simulation was shown (p<0.05). The results of histological studies show signs of the proliferative phase in the form of a significant number of fibroblasts and newly formed vessels, as well as the beginning of the remodeling stage in the form of the organization of collagen fibers in parallel bundles in the wound canals in different areas within 10 days. On the 20th day, the absence of inflammatory cells in the preparations of the damaged areas is noted. Also at the tissue level at this time, signs of the remodeling phase were revealed: a significant decrease in the number of blood vessels and fibroblasts was observed, the connective tissue in the areas acquired a mature appearance in the form of dense layers with single fibrocytes. In the injury zone on the 40th day of the experiment, scars from mature connective tissue were noted. Conclusion. In an experimental study, we showed the morphological and physiological features of the healing of soft tissue injuries in normal rats. The established structural features of wound areas at different stages of healing and the dynamics of IFN-γ release allow us to determine its important role not only in inflammation, but also in the stages of proliferation and remodeling. Determination of the concentration of IFN-γ may be an informative indicator at all stages of repair in the process of healing soft tissue injuries in humans, subjected to further clinical studies

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New Trauma Score versus Kampala Trauma Score II in predicting mortality following road traffic crash: a prospective multi-center cohort study

Damulira,

Muhumuza,

Kabuye

et al. 2024

BMC Emerg Med

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Introduction Mortality due to injuries disproportionately impact low income countries. Knowledge of who is at risk of poor outcomes is critical to guide resource allocation and prioritization of severely injured. Kampala Trauma Score (KTS), developed in 1996 and last modified in 2002 as KTS II, is still widely being used to predict injury outcomes in resource-limited settings with no further revisions in the past two decades, despite ongoing criticism of some of its parameters. The New Trauma Score (NTS), a recent development in 2017, has shown potential in mortality prediction, but a dearth of evidence exist regarding its performance in the African population. Objectives To compare NTS to the modified Kampala Trauma Score (KTS II) in the prediction of 30-day mortality, and injury severity amongst patients sustaining road traffic crashes in Ugandan low-resource settings. Methods Multi-center prospective cohort study of patients aged 15 years and above. Of the 194 participants, 85.1% were males with a mean age of 31.7 years. NTS and KTS II were determined for each participant within 30-minutes of admission and followed-up for 30 days to determine their injury outcomes. The sensitivity, specificity, and area under receiver operating characteristics curve (AUC) for predicting mortality were compared between the two trauma scores using SPSS version 22. Ethical clearance: Research and Ethics Committee of Kampala International University Western Campus (Ref No: KIU-2022-125). Results The injury severity classifications based on NTS vs. KTS II were mild (55.7% vs. 25.8%), moderate (29.9% vs. 30.4%), and severe (14.4% vs. 43.8%). The mortality rates for each injury severity category based on NTS vs. KTS II were mild (0.9% v 0%), moderate (20.7% vs. 5.1%), and severe (50% vs. 28.2%). The AUC was 0.87 for NTS (95% CI 0.808–0.931) vs. 0.86 (95% CI 0.794–0.919) for KTS II respectively. The sensitivity of NTS vs. KTS II in predicting mortality was 92.6% (95% CI: 88.9–96.3) vs. 70.4% (95% CI: 63.0-77.8) while the specificity was 70.7% (95% CI: 64.2–77.2) vs. 78.4% (95% CI: 72.1–84.7) at cut off points of 17 for NTS and 6 for KTS II respectively. Conclusions NTS was more sensitive but its specificity for purposes of 30-day mortality prediction was lower compared to KTS II. Thus, in low-resourced trauma environment where time constraints and pulse oximeters are of concern, KTS II remains superior to NTS.

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Clinical profile and outcomes of trauma patients visiting the emergency department of a trauma center Addis Ababa, Ethiopia

Cited by 4 publications

References 23 publications

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Histological Characteristics of Experimental Wounds of Soft Tissues of the Femur of Rats and the Role of IFN-γ in the Dynamics of their Healing

New Trauma Score versus Kampala Trauma Score II in predicting mortality following road traffic crash: a prospective multi-center cohort study

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