Clinical presentation of hypernatremic dehydration in exclusively breast-fed neonates

Yaseen, Hakam; Salem, Moza; Darwich, Maha

doi:10.1007/bf02829814

Cited by 34 publications

(23 citation statements)

References 12 publications

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“…7 Distribution of cases in our study are in agreement of above study but Zachariassen G et al in their retrospective study observed hypernetremic dehydration in newborns, in which 57% were born from primi gravida and 33% from multiparaous mother which is slightly lower than our study. 8 Penalver Giner O, Gisbert Mestra G et al in Spain in their retrospective study on full term exclusive newborn found hypernetremic dehydrated babies, 83% born from primiparous and 16% from multiparous which is higher than our study.…”

Section: Parameters Mean Change±sd P-value Significance Pt (Bf)-d (N=10)supporting

confidence: 92%

Study of renal functions in preterm and full term new born in relation to parity of the mother

Bhatnagar

Gupta

et al. 2016

Int J Res Med Sci

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Section: Parameters Mean Change±sd P-value Significance Pt (Bf)-d (N=10)supporting

confidence: 92%

Study of renal functions in preterm and full term new born in relation to parity of the mother

Bhatnagar

Gupta

et al. 2016

Int J Res Med Sci

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“…Decreased urine and stool frequency might be considered as a warning for failure of lactation. 7 Hypernatremia is lethal condition leads to cerebral edema, intracranial hemorrhage, seizures, disseminated intravascular coagulation and finally death. In our study 75% patients had hypernatremia could be due to insufficient feeding.…”

Section: Discussionmentioning

confidence: 99%

Clinical profile and outcome of neonates admitted during summer months with dehydration and hypernatremia in tertiary care hospital of central Gujarat, India

Shah

Javadekar

2018

Int J Contemp Pediatr

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Background: Dehydration and hypernatremia amongst exclusively breast fed neonates due to inadequate breast feeding or due to less feeding is a potentially devastating condition, and its incidence rate increases during hot environment especially during summer months. We conducted this study to identify possible etiology behind dehydration and hypernatremia among healthy newborn.Methods: Authors retrospectively studied from available records from our Extramural NICU for months of March, April, and May 2017. Inclusion criteria for study were 1) Neonates with signs and symptoms of dehydration, 2) exclusively breast fed newborn. Those with congenital malformations, very low birth weight and perinatal asphyxia were excluded from the study.Results: Total NICU admissions were 434 during these months, and 28 patients we received with dehydration and 21 patients out of 28 had hypernatremia. Incidence rate of dehydration was 6.45%. Almost all the patients had altered renal functions at the time of admission, which became normal before discharge. 4 patients had culture proven sepsis. 2 patients died out of 28 patients. 26 patients out of 28 recovered completely and discharged.Conclusions: Dehydration and hypernatremia is preventable and treatable condition. All the mothers needs to taught correct feeding method like proper position and attachment of feeding. Signs of dehydration must be explained to mother as well as close relatives. Follow up visits should be ensured and check for weight is must. Not to encourage mother to give any other feed apart from exclusive breast feeding for first 6 months and even during summer months.

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“…There were no systematic reviews focusing on specifics of treatment and its outcomes and no randomized clinical trials. There were 7 retrospective [10,[21][22][23][24][25] and 2 prospective studies [26,27] with ≥ 5 patients included. Only 2 articles performed direct comparisons regarding different treatments [10,22] ( Table 1 ), while the remaining studies described types of treatment and outcomes and were kept in the review for descriptive purposes only ( Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

Treatment of Hypernatremia in Breastfeeding Neonates: A Systematic Review

Bischoff

Dornelles²,

Carvalho

2017

Biomed Hub

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Background/Aims: Hypernatremic dehydration in term neonates is associated with inadequate fluid intake, usually related to insufficient lactation. The use of hypotonic fluids is appropriate to dilute serum sodium (SNa), but cerebral edema may develop when it happens abruptly. Our objective was to clarify how to correct hypernatremic dehydration properly. Methods: The following databases were searched, limited to studies published until January What Is It about?Hypernatremic dehydration in term neonates is classically associated with inadequate fluid intake, particularly in breastfed infants. Although the literature proposes a maximum rate of serum sodium (SNa) reduction, there is no consensus about proper rehydration strategies in hypernatremic neonates. Both the degree of hypernatremia and the rate of SNa drop during treatment are key players in the development of serious adverse effects. We highlight the importance of conducting well-designed studies in order to elucidate remaining questions. case series evaluating relevant outcomes. Information regarding the way of administering the treatment, type of fluid used, rates of complications and outcomes, as well as the rate of SNa reduction were collected. Results: Searches yielded 771 articles: 64 had the full text reviewed and 9 were included. No randomized clinical trials or systematic reviews focusing on treatment of hypernatremic dehydration and its outcomes were found. We found a scarcity of high quality studies and great methodology heterogeneity. Conclusions: More severe hypernatremia is at greater risk of causing severe adverse effects of treatment. There is no consensus about the optimal rate of SNa drop in this population, but a slower correction appears to be safer. Questions as when parenteral fluids are indicated remain unanswered.

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Clinical presentation of hypernatremic dehydration in exclusively breast-fed neonates

Abstract: Low level of maternal knowledge in lactation, cesarean section and failure of early postnatal follow up was associated with the neonatal dehydration. Decreased urine and stool frequency might be considered as a warning for failure of lactation.

Cited by 34 publications

References 12 publications

Study of renal functions in preterm and full term new born in relation to parity of the mother

Study of renal functions in preterm and full term new born in relation to parity of the mother

Clinical profile and outcome of neonates admitted during summer months with dehydration and hypernatremia in tertiary care hospital of central Gujarat, India

Treatment of Hypernatremia in Breastfeeding Neonates: A Systematic Review

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