Clinical presentation and CT/MRI findings of alveolar soft part sarcoma: a retrospective single-center analysis of 14 cases

Liu, Tian; Cui, Chun Yan; Lu, Shaoying; Cai, Pei; Xi, Shao Yan; Fan, Wei

doi:10.1177/0284185115597720

Cited by 12 publications

(9 citation statements)

References 22 publications

(24 reference statements)

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“…In this study, stripped necrosis of decentered distribution was found in a tumor with a diameter of 90 mm in 1 patient, which was consistent with a previous report [3]. The largesized decentered necrosis happened before non-necrosis happened in the center of the tumor.…”

Section: Discussionsupporting

confidence: 92%

Magnetic Resonance Features and Characteristic Vascular Pattern of Alveolar Soft-Part Sarcoma

Cui

Chen²,

Hao³

et al. 2017

Oncol Res Treat

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Objective: The aim of this study was to investigate the magnetic resonance (MR) features of alveolar soft-part sarcoma (ASPS). Methods: We studied 12 patients with ASPS confirmed by pathology in this retrospective study. MR features were analyzed, especially for the location, morphology, signals, and related enhanced features of the tumor vessels. Results: Flow voids were shown in the central part of the tumor on T2-weighted imaging (T2WI) in all patients; they were arrayed in a radiating mode gathered toward the center (8 cases), designated by us as vascular center-gathered syndrome (VCGS), or scattered like twigs (4 cases). The flow voids were accompanied by high signals in all patients, including tubular (6 cases) and platy (6 cases) signals. Slightly higher signals were shown in the peripheral part of the tumor in all patients. Flow voids in the peripheral part were shown in all patients, and the majority of the flow voids surrounded the tumor (8 cases). The vessels around the tumor in 9 patients showed high signals, and the majority of the vessels were located at the superior and inferior poles (8 cases). 6 patients underwent enhanced scanning, including moderate (5 cases) and significant enhancement (1 case). Conclusion: Low signals of radiating flow voids accompanied by high signals of slow blood flow or blood sinuses in the center part have high significance for the diagnosis of ASPS.

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Section: Discussionsupporting

confidence: 92%

Magnetic Resonance Features and Characteristic Vascular Pattern of Alveolar Soft-Part Sarcoma

Cui

Chen²,

Hao³

et al. 2017

Oncol Res Treat

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“…Intense enhancement and feeder vessels were also a commonly seen feature. Intense enhancement, presence of feeders, and multiple flow voids were the most consistent findings across many studies 4 9 10 11 12 16 ( Figs. 2 , 3 , 4 , and 5 ).…”

Section: Discussionsupporting

confidence: 64%

Imaging and Pathological Features of Alveolar Soft Part Sarcoma: Analysis of 16 Patients

Gulati

Mittal

Barwad

et al. 2021

Indian J Radiol Imaging

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Context Alveolar soft part sarcoma (ASPS) is a rare soft tissue tumor most commonly occurring in deep intramuscular plane of lower extremities of adolescents and young adults. It is a highly vascular, slow growing tumor with malignant potential having lung as the most common site of metastases at the time of presentation. Aims The aim is to review the imaging findings of ASPS and determine characteristic imaging features of this rare tumor. Materials and Methods Sixteen patients having histopathological diagnosis and preoperative imaging of ASPS attending the dedicated sarcoma clinic at our institute were included in the study. The demographic, clinical, and imaging data were retrieved from the case records and then evaluated for characteristic imaging features which may raise suspicion of ASPS. Results The patients ranged from 3 to 72 years of age and with a slight male preponderance. Of the eight CECTs evaluated, 62.5% tumors showed well-defined lobulated margins, 87.5% cases showed intense enhancement with presence of feeder vessels. On CEMRI of 10 patients, 70% had well circumscribed lobulated margins with intense enhancement and tortuous flow voids in most of them. All cases showed T2 hyperintense signal. Fourteen of 16 (87.5%) patients had metastatic disease with lung as the most common site (92.8%). Conclusion ASPS is a rare soft tissue sarcoma seen in children and young adults. Imaging may mimic a vascular malformation due to the presence of tortuous feeders. Misdiagnosis at an early stage may lead to later metastatic presentation of the disease, thus emphasizing the need to suspect it on imaging.

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“…ASPS are highly vascular tumors often presenting as pulsating masses with bruits. On imaging, ASPS are usually well-circumscribed lobulated masses with nodular architecture, moderately high T1 and T2 signal intensity, and intense heterogenous contrast enhancement with central necrosis [40]. Large vessels at the periphery converging centrally, multiple flow voids, and high signal intensity on T1 are characteristic imaging features [38][39][40][41].…”

Section: Selected Sarcomas Of the Head And Neckmentioning

confidence: 99%

“…On imaging, ASPS are usually well-circumscribed lobulated masses with nodular architecture, moderately high T1 and T2 signal intensity, and intense heterogenous contrast enhancement with central necrosis [40]. Large vessels at the periphery converging centrally, multiple flow voids, and high signal intensity on T1 are characteristic imaging features [38][39][40][41]. Although the appearance is similar to other aggressive soft tissue sarcomas, ASPS should be suggested when children or young adults present with a highly vascular mass, especially with concurrent lung metastases.…”

Section: Selected Sarcomas Of the Head And Neckmentioning

confidence: 99%

“…Although the appearance is similar to other aggressive soft tissue sarcomas, ASPS should be suggested when children or young adults present with a highly vascular mass, especially with concurrent lung metastases. ASPS has a high propensity for hematogenous metastases, most frequently to the lungs, bones and brain (Case 8) [40][41][42].…”

Section: Selected Sarcomas Of the Head And Neckmentioning

confidence: 99%

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Soft Tissue Special Issue: Imaging of Bone and Soft Tissue Sarcomas in the Head and Neck

Tran

Guenette

Jagannathan

2020

Head and Neck Pathol

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Bone and soft tissue sarcomas of the head and neck are a heterogenous group of tumors with overlapping features. Distinguishing between the various subtypes is challenging but necessary for appropriate diagnosis and management. The purpose of this article is to discuss the role of imaging in evaluating head and neck tumors, provide a general radiographic approach in differentiating between benign versus malignant lesions and give examples of selected subtypes of bone and soft tissue sarcomas in the head and neck with classic or pathognomonic imaging findings.

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Clinical presentation and CT/MRI findings of alveolar soft part sarcoma: a retrospective single-center analysis of 14 cases

Cited by 12 publications

References 22 publications

Magnetic Resonance Features and Characteristic Vascular Pattern of Alveolar Soft-Part Sarcoma

Magnetic Resonance Features and Characteristic Vascular Pattern of Alveolar Soft-Part Sarcoma

Imaging and Pathological Features of Alveolar Soft Part Sarcoma: Analysis of 16 Patients

Soft Tissue Special Issue: Imaging of Bone and Soft Tissue Sarcomas in the Head and Neck

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