2007
DOI: 10.1111/j.1365-4632.2007.03214.x
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Clinical, pathologic, and immunopathologic features of dermatitis herpetiformis: review of the Mayo Clinic experience*,

Abstract: In this large series of patients with DH from a single institution, patients had a low incidence of symptomatic gluten-sensitive enteropathy, low risk of lymphoproliferative disorders, and associations with other systemic autoimmune disorders. The value of DIF testing in the diagnosis of DH was confirmed. The detection of antiendomysial antibodies by indirect immunofluorescence was less sensitive than indicated by other reports.

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Cited by 123 publications
(107 citation statements)
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“…Additionally, it is accepted that all DH patients have CD in theory, due to sharing a common mechanism, even though they usually have subclinical gastrointestinal disease and only mild symptoms. In our DH patients, 37.5% were diagnosed with CD by histopathological examination, whereas this was reported as 3.3%-18% in the literature (13,22).…”
Section: Discussioncontrasting
confidence: 40%
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“…Additionally, it is accepted that all DH patients have CD in theory, due to sharing a common mechanism, even though they usually have subclinical gastrointestinal disease and only mild symptoms. In our DH patients, 37.5% were diagnosed with CD by histopathological examination, whereas this was reported as 3.3%-18% in the literature (13,22).…”
Section: Discussioncontrasting
confidence: 40%
“…In spite of reports that cardiovascular diseases were generally associated with BP, cardiovascular diseases were also associated with other ABDs in some case reports (13,22,24). Nevertheless, Marzano at al.…”
Section: Discussionmentioning
confidence: 92%
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“…[45] A recent large, retrospective study by Alonso-Llamazares et al found a 12.6% prevalence rate of CD and 22% prevalence rate of systemic autoimmune disorders among 263 DH patients. [46] Diagnosis is made by immunoflourescent visualization of granular IgA deposits at the junction of the epidermal/dermal layers in biopsies taken close to but not in an affected area. Epidermal tissue transglutaminase (eTg) is considered one of the key target autoantigens; the intestinal inflammation occurring in CD may be associated with increased production of antibodies directed against eTg.…”
Section: Dermatological Manifestationsmentioning
confidence: 99%