Clinical manifestations of Kawasaki disease shock syndrome: A case–control study

Abstract

Patients with KDSS may have uneven clinical course and may be misdiagnosed in the beginning. They may have more prominent inflammatory markers in the early phase and higher risk of coronary artery dilatation.

Kawasaki disease shock syndrome: three cases

“…Literature shows the disease is predominant in the 3-3.5 year age group but the cases reported here are older children 3 . Males have shown a preponderance and the clinical feature of erythematous rash was prominent 2 .…”

“…Males have shown a preponderance and the clinical feature of erythematous rash was prominent 2 . KDSS can also present without any of the typical features of KD 3 . Detecting and suspecting KDSS is difficult as it clearly mimics dengue shock syndrome, toxic shock and septic shock 2 .…”

“…The presence of high inflammatory markers with deranged liver function test can mislead the clinician. Performing 2D echocardiography early in the disease and having a suspicion of KDSS can help the clinician to pick this disease early 3 . The persistent nature of tachycardia prompted the clinicians to perform 2D Echocardiography in all three cases we report.…”

“…Possible causes for the haemodynamic instability are vasculitis with capillary leak, myocardial dysfunction and cytokine dysregulation 1 . KDSS may be misdiagnosed as it mimics other causes of shock 3 . It is important to have a high index of suspicion for KD in any child with prolonged fever of unknown origin and to refer to a paediatric facility promptly, as timely treatment reduces coronary artery damage 3 .…”

“…KDSS may be misdiagnosed as it mimics other causes of shock 3 . It is important to have a high index of suspicion for KD in any child with prolonged fever of unknown origin and to refer to a paediatric facility promptly, as timely treatment reduces coronary artery damage 3 . We report three cases of KDSS seen over a period of one year needing care in the high dependency and intensive care units.…”