Clinical manifestation and methods of treatment of pododermatitis in dogs

Abstract

This paper provides data on the clinical signs of pododermatitis in dogs and also investigates effective treatment regimens. The urgency of the stated problem is due to the growing incidence of pododermatitis in dogs, its polyetiological nature, which requires a multifaceted approach to diagnostics and the introduction of effective treatments methods. Thereby, the purpose of the study was to investigate the clinical manifestations of skin diseases of the distal extremities in dogs and to determine the efficacy of complex therapy of pododermatitis. The studies were based on clinical research methods in dermatology, parasitological (skin scraping), bacteriological, and mycological (seeding on nutrient media with subsequent isolation of the pathogen) surveys. Based on the findings of the study, the absolute number of cases revealed lesions of 2 paws (53.3%), much less often – all 4 limbs (26.7%). It was found that mainly localisation of superficial skin lesions was found in 56.2% in the area of the interdigital space and 43.7% of cases – only on the plantar surface of the pastern (metatarsus), rarely – inflammation of the claw phalanx (31.2%). The main clinical signs of dermatitis of the distal extremities in dogs were erosive and ulcerative inflammation, alopecia, papules and pustules filled with purulent exudate, erythematous inflammation, haemorrhage, areas of lichenification. Studies on the treatment of dogs with pododermatitis caused by Staphylococcus intermedius, Demodex canis and Malassezia pachydermatis have shown the following: introduction of drugs Bravecto, Cefuroxime, Orungal, Apoquel and Derinat increased the efficacy of therapy in animals of the experimental group, as compared with the control (from 28.6% to 66.7%), reducing the duration of treatment to 21 days (p˂0.01) and extending the remission period to an average of 185 days (p˂0.01). The prospect of further research is the unification of clinical, morphological, and biochemical blood parameters as diagnostic criteria for pododermatitis in dogs

Canine pododermatitis: A retrospective study of 300 cases

“…In canine pododermatitis the interdigital skin is most often affected (Broek and Horvath-Ungerboeck, 2011), as seen in the present and in a previous study (Yevtushenko et al 2021).…”

“…Also, parasitic infections (demodicosis, trombiculiasis, pelodera) are likely to involve all feet (Broek and Horvath-Ungerboeck, 2011;Miller et al, 2013). In a previous study, that included only 16 cases, two paws were mostly affected (53.3%), while all four legs were lesional in 26.7% of the dogs (Yevtushenko et al, 2021). On the contrary in our study more than half of the dogs presented skin lesions in all four feet.…”

“…In this study almost half of the dogs had secondary infections. Bacterial organisms were found more commonly than Malassezia, as it was also found the cases in a previous study (Yevtushenko et al 2021). Even though there are no data on their prevalence in canine pododermatitis, bacterial infection has been reported to be a significant component of interdigital furunculosis, pododemodicosis, leishmaniosis, skin neoplasia, trauma and foreign body-induced pododermatitis, which were some of the common primary causes in this study.…”

“…There are several review articles, many case reports and prospective studies on the medical and/or surgical therapy of canine pododermatitis. However, according to the authors knowledge, only two retrospective studies have been published (Chhabra et al, 2020;Yevtushenko et al,2021) that included only 99 and 16 cases, respectively, plus one large scale retrospective study on digital neoplasms (Grassinger et al, 2021). Therefore, the purpose of this retrospective study was to analyze a large number of dogs with pododermatitis and to investigate the possible associations between signalment, history, clinical and laboratory findings, with the primary and secondary causes.…”

Influence of heliogeophysical factors on patients with myocardial infarction

“…Similar results were obtained by American researchers for 4 years of studying mortality from coronary insufficiency and CSs (275 million indicators). 40 These studies did not reveal statistically significant linear correlations of medical and heliogeophysical parameters, which contributed to the emergence of serious skepticism towards this problem in the West. 41…”