Clinical isolates of Staphylococcus lugdunensis and S. schleiferi: bacteriological characteristics and susceptibility to antimicrobial agents

Staphylococcus hominis subsp. novobiosepticus subsp. nov., a novel trehalose- and N-acetyl-D-glucosamine-negative, novobiocin- and multiple-antibiotic-resistant subspecies isolated from human blood cultures

“…1 992-1993 1992-1993 infections, but has been generally regarded as a contaminant or low-grade opportunistic pathogen of immunocompromised patients (Nord et al, 1976;Sewell et al, 1982 ;Bowman & Buck, 1984;Fleurette et al, 1987;Kleeman et al, 1993;Kloos & Bannerman, 1994). This species has been frequently isolated from blood cultures, although it has been considered to be clinically significant in only a small proportion of cases (Bowman & Buck, 1984;Pulverer, 1985;Ponce de Leon et al, 1986;Kleeman et al, 1993).…”

Urinary tract infection due to Staphylococcus lugdunensis in a 70-year-old woman with cystocele grade 3

“…distinct from Staphylococcus aureus comprise the group known as coagulasenegative staphylococci (CoNS), so named for their inability to clot plasma due to the lack of production of the secreted enzyme coagulase (Bannerman & Peacock, 2007). Staphylococcus lugdunensis is a member of the CoNS and was first described in 1988 (Fleurette et al, 1989). S. lugdunensis is commonly found on the human skin and is a rare contaminant in cultures (Seenivasan & Yu, 2003).…”

“…S. lugdunensis is commonly found on the human skin and is a rare contaminant in cultures (Seenivasan & Yu, 2003). S. lugdunensis, named after Lyon, France, the city where the organism was initially isolated (Fleurette et al, 1989), has emerged as an important human pathogen with notable clinical and microbiological characteristics that stand out among those of other CoNS (Frank et al, 2008). Described previously as 'surreptitious' (Sotutu et al, 2002) and a 'wolf in sheep's clothing', S. lugdunensis behaves more like S. aureus than other CoNS in many respects, including exhibiting an elevated degree of virulence.…”

Specific Identification of Staphylococcus aureus by Staphychrom II, a Rapid Chromogenic Staphylocoagulase Test

“…However, this test requires 18 to 24 h of incubation and is not perfectly reliable (1,13,16,18). Agglutination tests with either erythrocytes or latex particles coated with various ligands may lack sensitivity, notably, for methicillin-resistant S. aureus (MRSA), and may also lack specificity for non-S. aureus staphylococci, such as S. lugdunensis, S. schleiferi, and S. intermedius (3,8,14,15).In the present study we evaluated Staphychrom II (International Microbio, Signes, France), a rapid (2-h) chromogenic staphylocoagulase test which specifically detects S. aureus, and compared the results obtained with those obtained by a reference TCT (Becton Dickinson, Le Pont de Claix, France) and the latex agglutination test (LAT) Slidex Staph Plus (bioMérieux, Marcy l'Etoile, France). The tests were compared prospectively with 293 clinical isolates in two clinical laboratories and retrospectively with 193 typical and atypical collection strains chosen because of their potential testing pitfalls.…”

“…However, this test requires 18 to 24 h of incubation and is not perfectly reliable (1,13,16,18). Agglutination tests with either erythrocytes or latex particles coated with various ligands may lack sensitivity, notably, for methicillin-resistant S. aureus (MRSA), and may also lack specificity for non-S. aureus staphylococci, such as S. lugdunensis, S. schleiferi, and S. intermedius (3,8,14,15).…”