Clinical implications of supraventricular arrhythmias in patients with severe pulmonary arterial hypertension

Ruiz-Cano, María J.; González‐Mansilla, Ana; Escribano, Pilar; Delgado, Juan; Arribas, Fernando; Torres, Juan Pablo; Flox, Angela; Riva, Marta; Gómez, Miguel Ángel; Saenz, Carlos

doi:10.1016/j.ijcard.2010.09.065

Cited by 64 publications

(90 citation statements)

References 7 publications

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“…Between these different patient populations there are consistently high rates of all supraventricular arrhythmias including atrial fibrillation (AF), atrial flutter and atrioventricular re-entrant tachycardia (AVNRT). Interestingly these studies have shown a similar distribution of the types of arrhythmias seen with approximately 40% of patients having atrial fibrillation, 40% flutter, 10% atrial tachycardia and 10% atrioventricular nodal re-entrant tachycardia [7][8][9]. In a study of patients with congenital heart disease and confirmed pulmonary hypertension due to the Eisenmenger reaction the majority were in sinus rhythm at the start of the study with only 2% of patients in atrial fibrillation.…”

Section: Reviewmentioning

confidence: 77%

“…atrioventricular re-entrant tachycardia) in PAH patients in two of the cohort studies described above [7,8]. This suggests that AVNRT is due to remodelling in response to PAH rather than due congenital abnormalities in conduction.…”

Section: Reviewmentioning

confidence: 97%

“…Cohort studies following groups of patients with either idiopathic PAH, all forms of PAH or a combined group of PAH and chronic thromboembolic pulmonary hypertension patients have shown a prevalence of arrhythmias of around 15-20% in world health organisation class III and IV PAH patients [7][8][9][10]. Between these different patient populations there are consistently high rates of all supraventricular arrhythmias including atrial fibrillation (AF), atrial flutter and atrioventricular re-entrant tachycardia (AVNRT).…”

Section: Reviewmentioning

confidence: 99%

“…A comparison of the relative distribution of the different types of arrhythmias seen in the PAH population with the general population shows that the ratio of atrial flutter:AF cases is approximately 1:5 in the general population whereas in the PAH populations it is close to 1:1 [7][8][9][10]18]. It is perhaps not surprising that atrial flutter is disproportionately more prevalent in patients with PAH.…”

Section: Reviewmentioning

confidence: 99%

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Arrhythmias in pulmonary arterial hypertension

Temple¹

2017

J Congenit Heart Dis

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Pulmonary arterial hypertension is a condition associated with raised right heart pressures and subsequent remodelling of the right atrium and ventricle with relative preservation of left heart function. There is a high incidence of arrhythmias including atrial fibrillation, atrial flutter and atrioventricular nodal re-entrant tachycardia. Despite recent advances in medical therapy for pulmonary arterial hypertension arrhythmias continue to have a high morbidity and mortality. Treatment includes medical therapy, cardioversion and catheter ablation.

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Section: Reviewmentioning

confidence: 77%

Section: Reviewmentioning

confidence: 97%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

See 2 more Smart Citations

Arrhythmias in pulmonary arterial hypertension

Temple¹

2017

J Congenit Heart Dis

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“…Five studies evaluated the incidence of atrial arrhythmias in patients with PH [5][6][7][8][9]. The cumulative incidence varied between 11.7% and 25.1% over periods of 6-13 years.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the prognostic value of electrocardiography parameters and heart rhythm in patients with pulmonary hypertension

et al. 2016

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Background: Several studies have analyzed arrhythmias in patients with pulmonary hypertension (PH) and increased P-wave duration was identified as a risk factor for development of atrial fibrillation (AF 79.4 ± 5.4 months (sinus rhythm), (p = 0.565). Conclusions: Atrial fibrillation predict adverse prognosis in patients with PH and a longer P-wave (> 0.11 s) is associated with shorter survival time. (Cardiol J 2016; 23, 4: 465-472)

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The spectrum and prevalence of arrhythmia in different clinical pulmonary hypertension groups in Chinese population

Xue

Yang

Zhao

et al. 2022

Clinical Cardiology

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Background Arrhythmia is not uncommon among pulmonary hypertension (PH) population, and may be associated with disease severity. Hypothesis To investigate different spectrums and prevalence of arrhythmias in different clinical PH groups in Chinese population. Methods Patients diagnosed with PH between April 15, 2019, and August 2, 2021, were enrolled prospectively. The prevalence of different types of arrhythmias in PH patients were calculated. Logistic regression analyses were conducted to determine independent predictors for arrhythmia. Results One thousand patients were enrolled. The prevalence of any arrhythmia, sinus node dysfunction, sinus tachycardia, atrial fibrillation, atrial flutter, other types of atrial tachycardia, atrioventricular block, and ventricular tachycardia is 44.4%, 12.2%, 15.2%, 8.1%, 4.1%, 10.2%, 7.1%, and 2.5%. Logistic regression analyses revealed that older age and larger right ventricle (odds ratio: 1.111 and 1.095, p < .05) were independently related with higher probability of supraventricular arrhythmia; Complicating with coronary artery disease, larger right ventricle, and increased left ventricular end‐diastolic diameter (odds ratio: 19.540, 1.106, and 1.085, p < .05) were independently correlated with sinus node dysfunction/atrioventricular block in patients with pulmonary arterial hypertension. Conclusions Nearly half of PH patients experienced at least one type of arrhythmia. The most common seen arrhythmias were supraventricular arrhythmia, sinus tachycardia, and sinus node dysfunction. Older age and larger right ventricle were independently related with higher probability of supraventricular arrhythmia; Complicating with coronary artery disease, larger right ventricle and increased left ventricular end‐diastolic diameter were independently correlated with higher probability of sinus node dysfunction/atrioventricular block in patients with pulmonary arterial hypertension.

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Clinical implications of supraventricular arrhythmias in patients with severe pulmonary arterial hypertension

Cited by 64 publications

References 7 publications

Arrhythmias in pulmonary arterial hypertension

Arrhythmias in pulmonary arterial hypertension

Evaluation of the prognostic value of electrocardiography parameters and heart rhythm in patients with pulmonary hypertension

The spectrum and prevalence of arrhythmia in different clinical pulmonary hypertension groups in Chinese population

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