Clinical impact of cardiac computed tomography derived three-dimensional strain for adult congenital heart disease: a pilot study

Shiina, Yumi; Inai, Kei; Takahashi, Tatsunori; Shimomiya, Yamato; Nagao, Michinobu

doi:10.1007/s10554-019-01691-w

Cited by 14 publications

(8 citation statements)

References 17 publications

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“…In the converted dynamic series, a spherical volume of interest (VOI) was drawn in the ascending aorta and distal sites of coronary arteries with a diameter of 2 mm (coronary segment #3 in the right coronary artery, #7-8 in the left anterior descending artery, #13-14 in the left circum ex artery, and the distal site of the major branches such as the diagonal, ramus, and obtuse marginal in case where signi cant myocardial ischemia was proven by myocardial perfusion imaging). Once VOI was activated, it automatically tracked the movement of the coronary artery, it automatically tracked with voxel in all phases 12 . CT value was then exported as a time-density curve in Microsoft Excel.…”

Section: Calculation Of Rcfimentioning

confidence: 99%

Resting coronary flow estimated by dynamic coronary CT angiography: Potential for use in the detection of plaque burden and myocardial ischemia

Ando

Nagao

Yamamoto

et al. 2021

Preprint

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Purpose We propose a resting coronary flow index (rCFI) estimated by dynamic coronary CT angiography (CCTA) for potential use in detecting coronary plaque burden and myocardial ischemia. Materials and Methods A total of 124 patients with stable coronary artery disease (CAD) who underwent CCTA were prospectively enrolled in this study. The original data set of dynamic CCTA with continuous 8 to 12 cardiac cycles was interpolated to 24 to 36 image sets using the motion coherence image processing. Using the maximum slope method, rCFI was defined as the ratio of the maximum upslope in the attenuation of distal coronary artery to that of the ascending aorta. Coronary plaques were classified as non-calcified or calcified based on the presence or absence of low attenuation plaque. For patients who may need additional functional assessment, additional stress/rest myocardial perfusion scintigraphy (MPS) was performed. Results rCFI for vessels with non-calcified plaques was significantly lower than that for normal arteries (0.73 ± 0.23 vs. 0.88 ± 0.22, p < 0.00001). In limited intermediate stenosis, a similar significant difference was observed between the two groups (0.76 ± 0.23 vs. 0.89 ± 0.20, p < 0.0001). In contrast, no significant decrease in rCFI was observed between normal and calcified plaques (0.81 ± 0.28). rCFI for ischemia depicted by MPS was significantly lower than for non-ischemia (0.63 ± 0.24 vs. 0.84 ± 0.19, p < 0.05). The use of the optimal cutoff could detect ischemia, with a C-static value of 0.73, 53% sensitivity, and 93% specificity. Conclusion rCFI can be used for the detection of plaque burden and myocardial ischemia in CAD.

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Section: Calculation Of Rcfimentioning

confidence: 99%

Resting coronary flow estimated by dynamic coronary CT angiography: Potential for use in the detection of plaque burden and myocardial ischemia

Ando

Nagao

Yamamoto

et al. 2021

Preprint

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“…Shiina et al published an interesting pilot study of CT based feature tracking and derived calculation of dyssynchrony. They plan to use this appealing approach in the planning of cardiac resynchronization therapies and for imaging its success in patients with congenital heart disease [108].…”

Section: Beyond the Coronaries: Ct Enters Myocardial Characterizationmentioning

confidence: 99%

Cardiovascular imaging 2019 in the International Journal of Cardiovascular Imaging

Reiber

Pereira

Dallan

et al. 2020

Int J Cardiovasc Imaging

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“…CTA-derived assessment of strain has emerged as a valuable method for the assessment of cardiac function, and it shows close correlations with both echocardiography and CMR [10][11][12][13]. The usefulness of CT-derived assessments of left ventricular strain in severe aortic stenosis [11], aortic valve stenosis [14], adult congenital heart disease [15] and myocardial infarction [16] has been reported. However, to the best of our knowledge, there have been no studies on CAD.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Regional Left Ventricular Myocardial Strain in Patients with Left Anterior Descending Coronary Stenosis Using Computed Tomography Feature Tracking

Han

Cao

et al. 2020

Preprint

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Background Computed Tomography feature tracking (CT-FT) has emerged as a valuable method for the assessment of cardiac function. However, there have been no study about the usefulness of CT-derived assessments of left ventricular strain on coronary artery disease (CAD). Our aim was to evaluate the regional left ventricular (LV) systolic deformation in patients with left anterior descending coronary (LAD) stenosis using CT-FT. Methods Seventy-six patients with LAD stenosis were enrolled. The patients were divided into four groups according to the percentage of LAD stenosis: ≤25% was defined as group I (24 patients), 26–49% as group II (17 patients), 50–74% as group III (21 patients), and ≥ 75% as group IV (14 patients).Thirty-two sex- and age-matched normal subjects were included as controls. Results No intergroup differences were found between groups I-IV and the controls in terms of the left ventricular ejection fraction, end-diastolic volume and end-systolic volume. However, the longitudinal strain (LS) of the LAD territory was significantly reduced in groups I-IV compared with the controls (-20.8% and − 18.5% and − 18.6% and − 17.0% vs -23.7%, respectively). The circumferential strain (CS) of the LAD territory was significantly reduced in groups III and IV compared with the controls and groups I and II (-22.4% and − 22.2% vs -25.4% and − 24.1% and − 25.3%, respectively). Compared with non-LAD territory, groups II-IV had significantly increased LS (-19.9% vs -21%; -18.6% vs -21.9%; -16.4% vs -20.1%). The severity of LAD stenosis had a positive correlation with the LS of the LAD territory (r = 0.438, p = 0.002). Conclusion CT‑FT can detect decreasing LV systolic function in patients with LAD stenosis. With the increasing severity of LAD stenosis, the LV regional systolic deformation of the LAD territory was reduced.

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Clinical impact of cardiac computed tomography derived three-dimensional strain for adult congenital heart disease: a pilot study

Cited by 14 publications

References 17 publications

Resting coronary flow estimated by dynamic coronary CT angiography: Potential for use in the detection of plaque burden and myocardial ischemia

Resting coronary flow estimated by dynamic coronary CT angiography: Potential for use in the detection of plaque burden and myocardial ischemia

Cardiovascular imaging 2019 in the International Journal of Cardiovascular Imaging

Assessment of Regional Left Ventricular Myocardial Strain in Patients with Left Anterior Descending Coronary Stenosis Using Computed Tomography Feature Tracking

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