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Background: Assessing endocardial strain using a single 13 N-ammonia positron emission tomography (PET) scan would be clinically useful, given the association between ischemia and myocardial deformation. However, no software has been developed for strain analysis using PET. We evaluated the clinical potential of feature tracking-derived strain values measured using PET, based on associations with the myocardial flow reserve (MFR). Methods and Results: This retrospective study included 95 coronary artery disease patients who underwent myocardial 13 N-ammonia PET. Semi-automatic measurements were made using a feature-tracking technique during myocardial cine imaging, and values were calculated using a 16-segment model. Adenosine-stressed global circumferential strain (CS) and global longitudinal strain (LS) values were compared with global MFR values. Stressed and resting global strain values were also compared. Global strain values were significantly lower in 39 patients with abnormal MFRs [<2.0] than in 56 patients with normal MFRsThe global CS values in the stressed state were significantly decreased than the resting state values in patients with abnormal MFRs. Conclusions:This study applied endocardial feature-tracking to 13 N-ammonia PET, and the results suggested that blood flow and myocardial motility could be clinically assessed in ischemic patients using a single PET scan.

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Triploid rainbow trout was compared with diploid one for the susceptibility to IHN, furunculosis and vibriosis, and for the effectiveness of vibrio vaccination.No differ ence was observed between the triploids and the diploids in the mortality or in the mean days to death when challenged with the pathogens of the diseases. Vaccinated triploids showed significantly lower mortality than triploids without vaccination when challenged with Vibrio ordalii, and there was no difference in the mortality between vaccinated dip loids and triploids. These results suggest that susceptibility to those infections and effectiveness of vibrio vaccination are principally the same for both diploid and triploid rain bow trout.