Clinical, histological and immunohistochemical features of ectomesenchymal chondromyxoid tumor

Pires, Fábio Ramôa; Abrahão, Aline Corrêa; Cabral, Márcia Grillo; Azevedo, Rebeca Souza; Horta, Martinho Campolina Rebello; Martins, Carlos Roberto; Almeida, Oslei Paes de; Chen, Sow‐Yeh

doi:10.1016/j.tripleo.2009.07.007

Cited by 22 publications

(30 citation statements)

References 13 publications

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“…The high positivity for S100 protein—a marker of myoepithelial cell—suggests chondromatous tissue in this condition 18 19. There was a negative immunoreaction of the tumour for the Pan-cytokeratin clone AE1/AE3, whose positivity would suggest tumours originating from epithelial cells 20.…”

Section: Discussionmentioning

confidence: 86%

Cartilaginous choristoma of the tongue with an immunohistochemical study

Pereira

Pereira²,

Pereira³

et al. 2012

BMJ Case Reports

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SummaryBy definition, choristomas are normal tissues found in anomalous topography. The cartilaginous features of these lesions are rare in the soft tissues of the oral cavity. The majority of cartilaginous choristomas of the tongue-the primary site of emergence of the oropharynx-are associated with adipose, fibrous or bone tissues-apart from that, only a few of these were confirmed by an immunohistochemical study. The neoplasm exclusively composed of chondromatous tissue is extremely rare in the tongue. This paper reports the clinical, surgical and pathological characteristics of a cartilaginous choristoma of the tongue diagnosed in a 64-year-old woman. BACKGROUND

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Section: Discussionmentioning

confidence: 86%

Cartilaginous choristoma of the tongue with an immunohistochemical study

Pereira

Pereira²,

Pereira³

et al. 2012

BMJ Case Reports

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“…[12] Some authors speculate that these areas of suspected atypia could in fact be associated with secondary inflammatory stimuli or aging of the tumors. [212] Mitotic figures are rare and necrosis is virtually absent. Few muscle fibers can be focally infiltrated by tumor cells, but does not seem to represent evidence of aggressive behavior.…”

Section: Review Of Literaturementioning

confidence: 99%

Ectomesenchymal chondromyxoid tumor: Review of literature and a report of a rare case

Mohanty

Narayan

Shenoy

et al. 2011

J Oral Maxillofac Pathol

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Ectomesenchymal chondromyxoid tumor (ECMT) is a rare benign intraoral tumor. Clinically, it presents as a slow growing, painless, firm, submucosal sweling exclusively occurring on the anterior dorsum of the tongue. Till date only 40 cases have been reported in literature. Histopathologically the tumor is characterized by a well circumscribed, lobular proliferation of round, polygonal, ovoid or fusiform cells in a net-like pattern in a myxoid to chondromyxoid background. Here, we present a rare case of ECMT occurring in a 7-year-old boy and throw some light on this distinct entity.

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“…However, the anterior portion of the tongue does not have a minor salivary gland and lacks myoepithelial cells 14. Moreover, ECMT usually lacks the expression of specific myoepithelial markers such as p63, smooth muscle myosin heavy chain, SMA, or calponin, which are generally expressed in myoepithelioma 9,11,13,15. Therefore, ECMT is considered a separate entity from myoepithelioma 14.…”

Section: Discussionmentioning

confidence: 99%

Ectomesenchymal Chondromyxoid Tumor in the Anterior Tongue: Case Report of a Unique Tumor

et al. 2012

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Ectomesenchymal chondromyxoid tumor (ECMT) is a rare tumor, exclusively arising in the anterior tongue. Thirty-eight cases have been reported in the English literature. It usually presents as a sessile protrusion and shows round to spindle cells embedded in myxoid to chondroid stroma. Tumor cells are almost always positive for polyclonal glial fibrillary acidic protein (GFAP). We report our experience in the recent treatment of a case of ECMT, the third case in 3 years. The mass in the anterior tongue revealed characteristic morphologic features of ECMT and the expression of polyclonal GFAP. Although ECMT should be differentiated from other mesenchymal tumors including myoepithelioma, its clinical, morphological, and immunohistochemical features enable its diagnosis, especially when pathologists are aware of it.

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Clinical, histological and immunohistochemical features of ectomesenchymal chondromyxoid tumor

Cited by 22 publications

References 13 publications

Cartilaginous choristoma of the tongue with an immunohistochemical study

Cartilaginous choristoma of the tongue with an immunohistochemical study

Ectomesenchymal chondromyxoid tumor: Review of literature and a report of a rare case

Ectomesenchymal Chondromyxoid Tumor in the Anterior Tongue: Case Report of a Unique Tumor

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