The respiratory intermediate care unit (RICU) is logistically a «step up» or «step down» unit between the intensive care unit (ICU) and general hospitalization. It is efficiency in terms of «avoided cost». During the pandemic, RICU increased exponentially with the aim of avoiding ICU congestion with coronavirus disease 2019 (COVID-19) patients. These units must be attended by a multidisciplinary professional team with presence and assistance 24 hours a day and must be prepared with adequate monitoring for a quick scale in case of deterioration. The high flow nasal cannula (HFNC) increases ventilator-free days and reduces hospital stays. Awake prone position significantly reduced the incidence of treatment failure. Conscious sedation is used to increase the tolerance to non-invasive ventilation (NIV). In the treatment with HFNC, obesity, immunosuppression and elevated inflammatory markers were associated with a higher failure rate. With everything learned so far, there should be no hospital without RICU.