Clinical Features of Pseudogout Attack

Calcium pyrophosphate dihydrate deposition in degenerate lumbar discs

“…Apart from one patient who presented with a long-standing history of knee pain and eventually underwent knee replacement, none of our patients had a history of general joint disorders or of pyrophosphate arthropathy (pseudogout), nor was there evidence of risk factors such as Chilean ancestry, hemochromatosis, hyperparathyroidism, true gout, or Wilson's disease [3,12]. Our patients were also younger than the typical patient population for pseudogout [10,13]. A higher prevalence of CPPD disease in women has been reported [3,13] but this was not the case in our study (male to female ratio 3 : 1).…”

“…However, patients may also present with an acute arthritis termed "pseudogout" [11] or chronic arthritic changes [3]. Typically the knee and wrist joints are involved [10,15].…”

The fate of acutely inflamed joints with a negative synovial fluid culture

“…Many conditions including crystal arthropathy and systematic diseases such as rheumatoid arthritis can present with an acutely inflamed joint [1,[12][13][14][15][16][17]. These conditions can have a clinical picture that may be indistinguishable from the clinical presentation of septic arthritis.…”

Preservation of calcium pyrophosphate dihydrate crystals: effect of Mayer's haematoxylin staining period

“…Additionally, we would like to note that a polarised light microscopic observation of a fresh wet coverslip preparation12 or a deparaffinised, unstained, coverslip preparation of a serial section, or that of histological specimens stained with safranin O/fast green/iron haematoxylin15 is also useful for identification of birefringent CPPD crystals in articular tissues.…”