Clinical features of gestational thrombocytopenia difficult to differentiate from immune thrombocytopenia diagnosed during pregnancy

Abstract

Gestational thrombocytopenia with platelet counts of less than 10 0000/μL occurred more frequently in twin pregnancies. Although onset of thrombocytopenia in the first trimester and a platelet count of less than 70 000/μL is more common in ITP, these findings were not uncommon in GT. Differentiation between ITP and GT may be feasible only with post-partum changes in the platelet count.

Maternal and fetal outcome among pregnant women presenting with thrombocytopenia

“…15 Kasai et al also did not report any neonate with APGAR score <7 at 5 minute. 25 In our study 8% of neonates were small for gestational age which was similar to a study conducted by Yuce et al in which 6.50% neonates were SGA.…”

“…In a study conducted by Lin et al and Kasai et al the age was similar to our study 39 weeks and 38 weeks respectively. 15,25 Where as in the study by Bouzari et al the age was 35.83+3.61 weeks which was lower than our study. 26 The mean platelet count in present study was 106907.7±30136.52/µL.…”

Severe primary autoimmune thrombocytopenia in pregnancy: a national cohort study

“…Figure S1 shows the diagram of information acquisition. Twenty‐eight papers reporting outcomes of ITP in pregnancy have been summarised in Table S4, and our UKOSS data have been included for comparison …”

Fetal-maternal complications and their association with gestational thrombocytopenia

“…We had no need for intravenous immunoglobulin (IVIG). Kasai et al [22], found that maternal treatment was required in 80% of immune thrombocytopenia subjects, but in none of the women with gestational thrombocytopenia, and the pregnancy outcomes were favorable in both groups, with no need for fetal treatment. Gernsheimer et al [21], recommend the use of corticosteroids or IVIG if platelet count falls below 20--30 × 10 9 /L.…”