Clinical Features of Bacteremia due to <i>Campylobacter jejuni</i>

Abstract

Objective The clinical features of bacteremia due to Campylobacter jejuni (C. jejuni) have yet to be fully elucidated. Methods and ResultsThe cases of C. jejuni bacteremia were retrospectively reviewed during a twelve-year period in a single institute. C. jejuni was identified in 7 patients through blood cultures, and disease onset occurred between June and October. Except for 2 previously healthy individuals, 5 patients had underlying diseases (chronic liver diseases, n=3; hematological malignancies, n=2). All patients were febrile, but 2 patients did not present with gastrointestinal symptoms. C. jejuni isolates were susceptible to gentamicin and macrolides, but about half of them were resistant to fluoroquinolones. Disease outcomes were favorable, and no deaths related to C. jejuni bacteremia were observed. Conclusion These results suggest that C. jejuni bacteremia could occur primarily or secondarily to gastroenteritis with a seasonal peak and that prognosis would be favorable regardless of the underlying diseases.

Campylobacter jejuniBacteremia in a Liver Cirrhosis Patient and Review of Literature: A Case Study

“…Microbiologically, C. fetus was found to be the most common strain (19/51, 37.3%) infecting these patients, followed by C. coli (17/51, 33.3%) and C. jejuni (11/51, 21.6%). C. upsaliensis, C. showae, and C. lari were also presented in several reports ( Table 2 ) [ 1 6 7 8 9 10 11 12 13 14 15 16 17 18 ]. Thus, if extra-intestinal symptoms manifest in a patient and a Gram stain of the blood sample suggests the presence of a Campylobacter spp., C. fetus, C. coli, or C. jejuni infection should be considered.…”

“…The global burden of disease and epidemiologic characteristics of Campylobacter bacteremia in Asian countries were unknown. Thus, we reviewed the reported cases of Campylobacter bacteremia, published between 2000 and 2014 ( Table 2 ) [ 1 6 7 8 9 10 11 12 13 14 15 16 17 18 ]. A total of 51 Campylobacter bacteremia cases were identified (Taiwan, 25; Japan, 16; Hong Kong, 8; Singapore, 1; Thailand, 1).…”

“…In general, the clinical symptoms of Campylobacter enteritis include diarrhea, abdominal pain and/or fever. In <0.1% of the cases, Campylobacter infection leads to extra-intestinal complications like Guillain-Barré syndrome [ 1 ].…”

Recurrent Campylobacter jejuni bacteremia in a patient with hypogammaglobulinemia

“…[7–12] In the past, it was believed that C. fetus was the cause of most systemic campylobacteriosis. Recent studies show, however, that both bacteremia and enterocolitis are caused mainly by C. jejuni .…”

Bacteriemia por Campylobacter jejuni en un paciente con infección por VIH en etapa SIDA

“…Puede cursar con otras manifestaciones digestivas como colecistitis, o extradigestivas como artritis o endocarditis; y complicaciones posteriores como síndrome de intestino irritable y síndrome de Guillain Barré 2 . De manera muy infrecuente se puede presentar con una bacteriemia, cuyo curso clínico puede ser más grave en pacientes con co-morbilidades como infección por VIH, daño hepático crónico, patologías hematológicas en quimioterapia, o infección por el virus de hepatitis C 2 .…”