“…In a study on 345 breast cancers, triple-negative cancer has a high histological grade, more metastasis, more local recurrence and contra-lateral breast cancers, and worse overall survival. 34 In our study, ER was negative in 207 cases (81.2%), with (57.6%) of them at clinical stage III, and 23.5% at stage II, with statistically highly significant relationship between the ER expression and the clinical stage at diagnosis (p ¼ 0.0001). It seemed that ER expression alone cannot predict outcome and this finding in our study was in agreement with a recent study that divided ER positive expression tumors into two subtypes.…”