Clinical Features and Presentation of Posterior Scleritis: A Report of 31 Cases

González-González, Luis; Molina-Prat, Nicolás; Doctor, Priyanka; Tauber, Joseph; Maza, Maite Sainz de la; Foster, C. Stephen

doi:10.3109/09273948.2013.840385

Cited by 50 publications

(37 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The current study showed female preponderance which was in accordance with the other case series on posterior scleritis. [ 5 6 7 8 ] Compared to other subtypes of scleritis, the posterior scleritis usually occurs in patients with relatively younger age. [ 3 9 ] The mean age of our patients in this study (41.2 years) was comparable to similar studies on posterior scleritis[ 7 ] and was in accordance with finding of the study by Lavric et al .,[ 5 ] where a relatively younger age of involvement in posterior scleritis was reported in Indian patients when compared with patients from the United Kingdom.…”

Section: Discussionmentioning

confidence: 99%

Clinical profile of patients with posterior scleritis: A report from Eastern India

Kumar

Ghose

Biswas

et al. 2018

Indian J Ophthalmol

View full text Add to dashboard Cite

Purpose:This study aimed to report the clinical profile of patients with posterior scleritis at a tertiary eye center in Eastern India.Methods:This was a single-center retrospective case series of patients who were diagnosed as posterior scleritis between January 2010 and December 2014, with a follow-up period of at least 6 months.Results:The study included 18 patients of posterior scleritis with a mean age of 41.2 ± 10.6 years (range: 26–63 years). With female preponderance (55.6%), majority of the posterior scleritis cases were unilateral (88.9%). Sixteen patients reported with diminution of vision, eleven patients (61.1%) had ocular pain on presentation, and five patients complained of headache. Concurrent anterior scleritis was found in three eyes (15%) with posterior scleritis. Choroidal folds and subretinal fluid at the posterior pole were the most common fundus findings and were seen in seven eyes (35%) each. No systemic association was detected in any patient even after extensive laboratory workup and multidisciplinary consultation. All patients received oral steroid, and 11 (61.1%) of them required intravenous pulse steroid therapy. Immunosuppressive was used in 6 (33.3%) patients, and oral azathioprine was the most common immunosuppressive used in the study. Recurrence was noted in eight eyes (40%). The mean best-corrected visual acuity improved to logarithm of the minimal angle of resolution (logMAR) 0.06 ± 0.051 at the final follow-up from 0.47 ± 0.45 logMAR at presentation (P = 0.00608).Conclusion:Posterior scleritis is relatively rare but can occur without systemic involvement. Aggressive immunomodulatory therapy is required to treat vision-threatening condition.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical profile of patients with posterior scleritis: A report from Eastern India

Kumar

Ghose

Biswas

et al. 2018

Indian J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Posterior scleritis may cause serous retinal detachments, optic disc edema, and chorioretinal granulomas. 46,99 …”

Section: Posterior Scleritismentioning

confidence: 98%

“…Four to ten percent of scleritis is infectious in origin, 46,92,133 with recent surgery and trauma as the most common cause. 27,55,59, 148 Post-surgical and post-traumatic causes of scleritis are generally bacterial in nature, upwards of 45% of all cases.…”

Section: Infectious Scleritismentioning

confidence: 99%

See 1 more Smart Citation

Treatment and management of scleral disorders

Diaz

Sobol

Gritz

2016

Survey of Ophthalmology

View full text Add to dashboard Cite

“…The first presentations, including loss of vision accompanied by pain in the eye, suggested in fact ON [8] or posterior scleritis (PS) [9].…”

Section: Discussionmentioning

confidence: 99%

Differentiating Vogt-Koyanagi-Harada syndrome from recurrent optic neuritis: a case report and review of the literature concerning Hispanic patients

Scarioni

Pietroboni

Invernizzi

et al. 2017

Mult Scler Demyelinating Disord

View full text Add to dashboard Cite

Background: First recognized at the beginning of twentieth century and named after three authors who independently described some affected patients, Vogt-Koyanagi-Harada syndrome is a rare multisystemic autoimmune disease targeting melanin-containing tissues of the eye, meninges, inner ear and skin. It predominantly affects Asian people, but also people with darker skin pigmentation such as Native Americans and Hispanics (Mestizos), whose ancestors moved from Asia across the Bering strait to North America and further down to Central and South America. Heterogenous presentation is observed, especially among different ethnic groups. Here we describe the case of an Hispanic South American patient presenting with multiple visual relapses and thus mimicking recurrent optic neuritis; we provide insights into the differential diagnosis and a brief review of the literature concerning the epidemiology of Vogt-Koyanagi-Harada syndrome in Hispanic patients compared with other ethnic groups. Case presentation: A 34-year-old Ecuadorian woman presented over years with multiple relapses involving the visual system. She was investigated in both neurologic and ophthalmic clinical settings. Brain Magnetic Resonance Imaging, cerebrospinal fluid examination, Spectral Domain Optical Coherence Tomography and Fluorescein Angiography were performed. She was misdiagnosed first as an optic neuritis pointing to a demyelinating disorder, then as a posterior scleritis. Due to the protean manifestations of Vogt-Koyanagi-Harada syndrome and the incomplete clinical presentation at the beginning, the right diagnosis was made only at a later disease stage using retrospective criteria. Conclusions: Hispanic patients often present without extraocular symptoms in early phases of the disease and they have globally lower rates of intertegumentary signs compared to Asian patients. The diagnosis of a multisystemic disease such as Vogt-Koyanagi-Harada syndrome is a challenge involving specialists operating in different medical fields; especially in urban multiethnic populations, rare etiologies of common symptoms have to be taken into account when performing a differential diagnosis.

show abstract

Clinical Features and Presentation of Posterior Scleritis: A Report of 31 Cases

Abstract: Posterior scleritis must be considered in patients with decrease of vision, mild to severe pain, optic disc edema, and/or posterior uveitis. Moderate to severe pain may be associated with poorer visual outcome.

Cited by 50 publications

References 12 publications

Clinical profile of patients with posterior scleritis: A report from Eastern India

Clinical profile of patients with posterior scleritis: A report from Eastern India

Treatment and management of scleral disorders

Differentiating Vogt-Koyanagi-Harada syndrome from recurrent optic neuritis: a case report and review of the literature concerning Hispanic patients

Contact Info

Product

Resources

About