Clinical features and natural course of Behçet’s disease in 661 cases: a multicentre study

Abstract

Mucocutaneous lesions are the hallmarks of the disease, and especially oral ulcers precede other manifestations. The increase in clinical severity score is more pronounced in patients without regular treatment and follow-up. Male sex and a younger age at onset are associated with more severe disease.

HLA-B51 subtypes in Turkish patients with Behçet's disease and their correlation with clinical manifestations

“…Considering the clinical findings in the BD patients, 100% had OUs, 82.4% had GUs, 47.1% had joint involvement, and 35.3% had ocular involvement and EN, consistent with previous studies (Tursen et al, 2003;Alpsoy et al, 2007Alpsoy et al, , 2012. The GUs were more frequent in the female patients, which is consistent with an earlier study, in which the clinical findings of 2313 patients were analyzed (Tursen et al, 2003).…”

“…The frequency of pathergy positivity in patients living in Mediterranean countries (84-98%) was suggested to be higher than the patients living in Far East (40-70%) (Lee et al, 1997;Alpsoy et al, 1998;Varol et al, 2010). The pathergy test was positive in 74.5% of our patients, which is higher than the results of other authors (56.1%) (Tursen et al, 2003;Alpsoy et al, 2007).…”

“…The frequency of PPLs was found to be 55.4 and 54.0% in two other study populations (Tursen et al, 2003;Alpsoy et al, 2007). When the subtypes were analyzed, PPLs were significantly lower in the HLA-B5109-positive patients.…”

Behçet's disease: rare systemic vasculitis in Poland

“…10 A younger age at onset has also been associated with a more severe disease course. 11 Panuveitis was the most common type of uveitis among both men and women with BD, although anterior uveitis was seen more frequently in women. 12 Male patients with younger age at onset and worse visual acuity at presentation have a higher risk of visual loss over time.…”

Colon Cancer Arising in an Ulcer Scar due to Intestinal Behcet's Disease

“…The prevalence of gastrointestinal involvement of Behçet's Disease is reported to be 1.4 to 1.5% (1,2). Single or multiple ulcers that are deep and penetrating to the serosal surface, like gastric peptic ulcers, are most commonly found in the ileocecal region (3).…”