Clinical evidence on potential health benefits of berries

Maesa indica: a nutritional wild berry rich in polyphenols with special attention to radical scavenging and inhibition of key enzymes, α-amylase and α-glucosidase

“…This effect delayed the degradation of starch and oligosaccharides, which in turn caused a decrease in the absorption of glucose and consequently inhibited the increase in postprandial blood glucose (Lee et al 2010). Several other berries have also shown promising activity via various mechanism of action earlier (Yang and Kortesniemi 2015). Hence, from the results, the consumption of M. indica fruit could effectively reduce the levels of a-amylase and a-glucosidase and significantly decrease the postprandial increase of blood glucose level.…”

“…It has been reported that quercetin, quercetin derivatives and phenolic compounds chlorogenic acid and caffeic acid greatly reduces oxidative damages and chronic diseases like diabetic, cardiovascular, proliferative and inflammatory related diseases (Zhang et al 2008). Further, all the berry fruits such as lingonberry (Vaccinium vitis-idaea), bilberry (Vaccinium myrtillus), cranberries (Vaccinium oxycoccos), black currant (Ribes nigrum), black raspberry (Rubus occidentalis), blueberry (Vaccinium corymbosum), chokeberry (Aronia melanocarpa), cranberry (Vaccinium macrocarpon), sea buckthorn berry (Hippophae rhamnoides), strawberry (Fragaria 9 ananassa), wolfberry (Lycium barbarum) possess enormous amount of flavonoid like rutin, quercetin and anthocyanin compounds with potential radical scavenging, antioxidant, anti-inflammatory and anti-diabetic properties (Joseph et al 2014;Yang and Kortesniemi 2015). The present HPLC result proved the fruit extracts of M. indica possess flavonoid, phenolics and their derivatives.…”

Efeito dos compostos fenólicos do camu-camu e do cupuaçu no desenvolvimento da obesidade e diabetes mellitus tipo 2

“…Health benefits of these classes of polyphenols include their antioxidant, anti-inflammatory, anti-obesity and anti-diabetic effects (Nile & Park, 2014;Dragan, Andrica, Serban, & Timar, 2014;Yang et al, 2015). Here, we demonstrated that supplementation of CCPE can decelerate the weight gain and attenuate metabolic disarrangements induced by HF/HS diet.…”

“…Among these metabolic effects could be the enhancing fat oxidation in adipose tissue and skeletal muscle (Dragan, Andrica, Serban, & Timar, 2014), the increasing of glucose utilization (Eid, Brault , Ouchfoun, & Thong, 2014;Hajiaghaalipour, Khalilpourfarshbafi, & Arya, 2015), and the attenuation on inflammatory responses and the suppression on oxidative stress (McDougall & Stewart, 2012, Yang & Kortesniemi, 2015. Further analyses are needed to elucidate the involved mechanisms for the prevention of weight gain in this study.…”

“…Among fruits, berries are reported as being a good source of dietary fiber, minerals, vitamin C and polyphenols, which are suggested to play a role in health benefits of fruit and vegetables based diets Heyman et al, 2014). In addition, recent clinical evidence indicates that intake of berries and their products may improve plasma lipid profile, reduce chronic inflammation and ameliorate postprandial glycemic response, specially in population with increased risk for metabolic syndrome development (Puupponen-Pimia¨ et al, 2013;Yang & Kortesniemi., 2015). These effects were associate with several classes of polyphenols present in berries such as anthocyanins, ellagitannins, flavan-3-ols, procyanidins, flavonols and hydroxybenzoate derivatives (Del Rio, Borges, & Crozier, 2010).…”