Clinical, endocrine and ultrasonographic features of polycystic ovary syndrome in Thai women

Abstract

The prevalence and clinical presentations of Thai women with PCOS were similar to those in other reports. However, hirsutism, elevated testosterone level and acanthosis nigricans were uncommon in our population. Serum androstenedione was a more sensitive indicator of hyperandrogenemia than total testosterone. Further research is needed to clarify whether there is an ethnic difference in endocrine profiles and risks of metabolic syndrome.

Ratio of ovarian stroma and total ovarian area by ultrasound in prediction of hyperandrogenemia in reproductive‐aged Thai women with polycystic ovary syndrome: A diagnostic test

“…Our result implied that biochemical hyperandrogenism consistently presented, while clinical hyperandrogenism varied among different PCOS populations. Compared with another study from Thailand reported by Vutayavanich et al ., our patients had lower prevalence of clinical hyperandrogenism (48.6% vs 61.3%) but higher prevalence of biochemical hyperandrogenism (81.1% vs 37.1%) . The differences between Vutayavanich et al .…”

“…Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged Thai women with a prevalence of 5-7%. 1 The diagnosis is based on the 2003 Revised Rotterdam criteria which focuses on history of menstruation, clinical or biochemical hyperandrogenism, and ultrasonographic features of the ovaries. 2 PCOS is a heterogeneous disorder of unexplained hyperandrogenism and chronic anovulation.…”

Correlation of clinical and biochemical hyperandrogenism in Thai women with polycystic ovary syndrome

“…One limitation of this trial is that we did not report androstenedione as the marker of hyperandrogenemia. A previous study in Thai PCOS women showed minority of this population had high level of androstenedione …”

“…A previous study in Thai PCOS women showed minority of this population had high level of androstenedione. 33 An mFG score of 6-8 is generally used to define hirsutism. 19 In our population, we found that the mFG score of 8 was the best cut-off point to predict hyperan drogenemia.…”

Defining polycystic ovary syndrome phenotype in Vietnamese women

“…Studies among mixed ethnic groups in the United States have included small numbers of Asian subjects and lacked information regarding their geographic origins . East Asians generally have lower rates of hirsutism and a higher prevalence of metabolic syndrome compared to Caucasian, Hispanic and African American patients . Asia is a massive continent with ethnic heterogeneity, and therefore each group must be studied separately in order to have reliable information regarding phenotypic manifestations of PCOS.…”