Clinical diagnosis of fissure caries with conventional and laser-induced fluorescence techniques

Chu, Chun Hung; Lo, Edward Chin Man; You, Dsh

doi:10.1007/s10103-009-0655-6

Cited by 58 publications

(59 citation statements)

References 25 publications

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“…The LF device had provided results than the radiographic method according to the assessment of sensitivity, specificity, accuracy, AUC, and likelihood ratio values. (12,21,22,27 or various other reasons. The radiographic method and the LF device supplied more diagnostic information than the visual method.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Diagnostic Tests Using Information Theory for Multi-Class Diagnostic Problems and its Application for the Detection of Occlusal Caries Lesions

Arslan¹,

Karaağaoğlu²,

Özkan³

et al. 2014

Balkan Med J

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Diagnostic tests are widely used in medical science for diagnosing the presence or absence of a disease. These tests may not discriminate between subjects with and without the disease or disorder with perfect accuracy. Several methods are available to evaluate the performance of diagnostic tests when the purpose of the test is to discriminate between two possible disease states. Different performance indices have been proposed to determine the accuracy of diagnostic tests when both the disease state and the test result are binary. However, in some cases, the disease state may have more than two categories. For this reason, there is a need for other methods to characterize the accuracy of diagnostic tests. In this study, we propose a method which is useful in terms of selecting the most appropriate diagnostic test when the disease state and test results have three or more classes. In this study, information content (IC) and proportional reduction in diagnostic uncertainty (PRDU) were introduced as measures of diagnostic test accuracy. To demonstrate the applicability of these statistics, we evaluated the diagnostic performance of four different diagnostic methods which are used for dental caries detection: visual inspection, radiography, laser fluorescence (LF) and micro-computed tomography (M-CT) examination.Background: Several methods are available to evaluate the performance of the tests when the purpose of the diagnostic test is to discriminate between two possible disease states. However multi-class diagnostic problems frequently appear in many areas of medical science. Hence, there is a need for methods which will enable us to characterize the accuracy of diagnostic tests when there are more than two possible disease states. Aims: To show that two information theory measures, information content (IC) and proportional reduction in diagnostic uncertainty (PRDU), can be used for the evaluation of the performance of diagnostic tests for multi-class diagnostic problems that may appear in different areas of medical science. Study Design: Diagnostic accuracy study. Methods: Sixty freshly extracted permanent human molar and premolar teeth suspected to have occlusal caries lesions were selected for the study and were assessed by two experienced examiners. Each examiner performed two evaluations. Histological examination was used as the gold standard. The scores of the histological examination were defined as sound (n=11), enamel caries (n=22) and dentin caries (n=27). Diagnostic performance of i) visual inspection, ii) radiography, iii) laser fluorescence (LF) and iv) micro-computed tomography (M-CT) caries detection methods was evaluated by calculating IC and PRDU. Results: Micro-computed tomography examination was the best method among the diagnostic techniques for the diagnosis of occlusal caries in terms of both IC and PRDU. M-CT examination supplied the maximum diagnostic information about the diagnosis of occlusal caries in the first (IC: 1.056; p<0.05), (PRDU: 70.5%) and second evaluation (IC: 1.105; p<0.05),...

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Section: Discussionmentioning

confidence: 99%

Evaluation of Diagnostic Tests Using Information Theory for Multi-Class Diagnostic Problems and its Application for the Detection of Occlusal Caries Lesions

Arslan¹,

Karaağaoğlu²,

Özkan³

et al. 2014

Balkan Med J

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“…6 Other investigators have reported PlgAChi NPs to be safe even at much higher concentrations of 20 mg/ml. [33][34][35] In addition, other research groups revealed interesting cytotoxicity results of chitosan NPs effect on human skin keratinocytes HaCaT cells. Tretinoin containing chitosan solid lipid NPs were not cytotoxic to HaCaT cells even at the highest concentration 500 μg/ml used, which led to around 5 % less viability compared with the control.…”

Section: Original Articlesmentioning

confidence: 99%

Untitled

2017

EDUJ

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“…13 Later on, some other researchers mainly focused on detection of occlusal secondary caries and caries around amalgam restoration margins. [14][15][16] Considering the importance of detecting secondary caries adjacent to composite restorations in the proximal areas (particularly in the gingival floor), the current study focused on this particular area. To the best of our knowledge, similar previous studies focusing on this topic are scarce.…”

Section: In Vitro Comparison Of Diagnostic Accuracy Of Diagnodent Andmentioning

confidence: 99%

In Vitro Comparison of Diagnostic Accuracy of DIAGNOdent and Digital Radiography for Detection of Secondary Proximal Caries Adjacent to Composite Restorations

et al. 2017

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Introduction: Early detection of secondary proximal caries is critical for the preservation of tooth vitality. This study sought to assess and compare the diagnostic accuracy of DIAGNOdent and digital radiography for detection of secondary proximal caries adjacent to composite restorations. Methods: Sixty extracted molars including 30 teeth with carious lesions and 30 sound teeth were randomly selected. Class II cavities were prepared in all teeth and carious dentin was intentionally left in the gingival floor of cavities in 30 carious teeth. All cavities were restored with composite resin. The teeth were mounted in wax blocks (three teeth per block) and examined for caries using (DIAGNOdent kaVo Dental, Biberach, Germany). Digital radiographs using DIGORA photostimulable phosphor (PSP) plates (Soredex Corporation, Helsinki, Finland) were obtained from all teeth using the parallel technique and were evaluated by 4 observers. Repeated measure analysis of variance (ANOVA) was applied to calculate sensitivity and specificity values of the two diagnostic techniques. Receiver operating characteristic (ROC) curve was plotted for DIAGNOdent results and based on that, the cutoff points were determined. Results: The sensitivity and specificity values at the cut-off point of 10.5 were 0.622 ± 0.038 and 0.822 ± 0.077 for DIAGNOdent and 0.591 ± 0.093 and 0.891 ± 0.083 for digital radiography, respectively. The area under the ROC curve was 0.7 for DIAGNOdent. Weighted kappa revealed moderate to almost perfect intra-observer agreement (0.46-0.99). Intraclass correlation coefficient (ICC) for DIAGNOdent was calculated to be 0.88. Conclusion: No statistically significant difference was noted in diagnostic accuracy of DIAGNOdent and digital radiography for detection of secondary proximal caries adjacent to composite restorations. Thus, DIAGNOdent may be used as an adjunct diagnostic tool for detection of secondary proximal caries beneath composite restorations.

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Clinical diagnosis of fissure caries with conventional and laser-induced fluorescence techniques

Cited by 58 publications

References 25 publications

Evaluation of Diagnostic Tests Using Information Theory for Multi-Class Diagnostic Problems and its Application for the Detection of Occlusal Caries Lesions

Evaluation of Diagnostic Tests Using Information Theory for Multi-Class Diagnostic Problems and its Application for the Detection of Occlusal Caries Lesions

Untitled

In Vitro Comparison of Diagnostic Accuracy of DIAGNOdent and Digital Radiography for Detection of Secondary Proximal Caries Adjacent to Composite Restorations

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