“…35 In concert with this boom in nutraceutical applications
of curcumin, DSHEA (Dietary Supplement Health and Education Act) legislation
establishing the legalities of dietary supplements in the United States
(1994) and advents in in vitro testing likely contributed significantly
to a sharp upturn in the publication of manuscripts regarding the
use of curcumin in biological studies in the late 1990s (Figure 2). Since that time,
curcumin has been reported to have activity for the following indications:
anti-inflammatory, anti-HIV, antibacterial, antifungal, nematocidal,
antiparasitic, antimutagenic, antidiabetic, antifibrinogenic, radioprotective,
wound healing, lipid lowering, antispasmodic, 36 antioxidant, 37 immunomodulating, anticarcinogenic, 38 and Alzheimer’s disease, 39 among others. In many scientific and medicinal circles,
these reported effects of curcumin have marked it as a source of future
breakthrough therapeutics for complex diseases that are thought to
require potent but nonselective therapeutics.…”