Clinical, cytological and histopathological evaluation of mammary masses in cats from Rio de Janeiro, Brazil

Abstract

The vast majority of mammary tumors in cats are malignant with high metastatic and mortality rates. This study evaluated clinical, cytological and histopathological aspects of 20 cases of cat mammary masses deriving from the city of Rio de Janeiro. Data on history, macroscopic description, evidence of regional lymph node and distant metastases, clinical examination and treatment were collected. The cats were treated with unilateral mastectomy, unilateral mastectomy plus chemotherapy or chemotherapy alone. Tissues were submitted for cytological and histological evaluation. Histopathological analysis described one case of mammary hyperplasia and 19 cases of adenocarcinoma. Inadequate surgical margins were obtained in two cats while six showed evidence of microscopic invasion in other mammary glands. Multiple mammary involvement and greater tumor size (diameter over 7.05 cm) were correlated with increased chance of local metastases. Ulceration of tumors and metastases were common. These facts support the highly malignant nature of this neoplasia and emphasize the risks associated with delay in diagnosis and treatment of feline patients. In conclusion, mammary palpation should be performed routinely in the clinical practice.

Estudo retrospectivo de 207 casos de tumores mamários em gatas

“…Para Brondey (1970) todas as glândulas mamárias de gatas possuem igual susceptibilidade para desenvolvimento de tumores mamários. Neste estudo, o grupo mamário G1 foi mais acometido do que o G2, concordando com Costa (2010) e divergindo de outros resultados encontrados em gatas (Travassos 2004, Amorim et al 2006) e em cadelas (Hayes et al 1981, Oliveira Filho et al 2010, nas quais as glândulas distais (G2) foram as mais atingidas. Numerosos casos neste estudo tinham ambos os grupos afetados, demonstrando assim que é relativamente comum na espécie felina a existência de múltiplos tumores mamários (Hayes & Mooney 1985, Misdorp 2002.…”

With Surgical Removal or Adjuvant Chemotherapy Increase the Two-Year Survival and Associated Clinicopathologic Factors in Cats With Mammary Carcinomas

“…Feline mammary tumors account for approximately 17% of all feline neoplasms, with most of them being malignant. [1][2][3][4][5] The high incidence of malignant potential may in°uence the clinicians' or owners' decision on the necessity for further treatment of feline mammary carcinoma (FMC). Similarly, due to the high incidence of malignancy in mammary tumors, there have been a vast number of studies investigating on the treatments and prognostic factors in cats with FMCs.…”

Caracterização histopatológica de tumores mamários espontâneos de gatas (Felis catus) atendidas no Hospital Veterinário da UFRPE (Recife, Pernambuco, Brasil)

“…O carcinoma da glândula mamária da gata é o mais comum em qualquer outra espécie animal, com exceção do cão. Este tipo de tumor corresponde a 17% de todos os tumores que acometem a gata (Amorim et al, 2006;Magalhães et al, 2009). Os carcinomas mamários ocorrem em gatas mais velhas, entre oito e doze anos de idade, com média, dez anos.…”

“…Os carcinomas mamários ocorrem em gatas mais velhas, entre oito e doze anos de idade, com média, dez anos. Não há predisposição racial estabelecida, embora alguns autores citem que em gatos siameses há o risco duas vezes maior do que todas as outras raças, além de desenvolver tumores mais precocemente (Amorim et al, 2006;Magalhães et al, 2009).…”