Clinical course, treatment, and multivariate analysis of risk factors for pyogenic liver abscess

Diabetes Mellitus and Pyogenic Liver Abscess: Risk and Prognosis

“…The validity of all of our estimates depends on the accuracy of the hospital discharge diagnoses used to identify cases of PLA and diabetes. Patients with PLA usually have severe symptoms, including abdominal pain, fever, and malaise, and are thus unlikely to avoid hospitalization [9,17]. Still, the onset of PLA may be insidious, with unspecific symptoms, and patients may die before a diagnosis is made [10,22].…”

“…We compiled a complete hospitalization history for each patient with PLA and each population control subject to assess medical or surgical risk factors for PLA that also may be associated with diabetes [5,7,9,10,17,18]. The following medical conditions were considered to be risk factors for PLA if they had been recorded as discharge diagnoses before or on the index date: benign biliary obstruction, liver cancer (including metastases to the liver), biliary tract cancer, pancreatic cancer, other gastrointestinal cancers, all other solid-organ cancers, hematological cancers, liver cirrhosis, inflammatory bowel disease, alcoholism, ongoing abdominal infection (acute cholecystitis or cholangitis without cholelithiasis, diverticulitis, appendicitis, or peritonitis), and ongoing systemic infection (sepsis or endocarditis).…”

Laparoscopic Drainage of Pyogenic Liver Abscesses

“…3 The advent of precise localization with imaging made imageguided percutaneous drainage (PCD) possible and decreased mortality by 10%-40%, 5,9 despite the published high failure rate of 36% for percutaneous drainage. 10 Contraindications for PCD include the presence of ascites, the proximity of vital structures, a bleeding tendency, and coexisting medical conditions requiring surgical itnervention.…”

“…It is commonly encountered in tropical areas 1,2 with an incidence varying from 0.006% to 2.2% of hospital admissions depending on the region. 3 Mortality rates have decreased remarkably in the last decade due to advances in imaging studies and antibiotics. 4,5 Broadtomy.…”

An experimental model for Staphylococcus aureus hepatic abscess in Bama minipig

“…The abscess prophase (inflammation stage) was found after 15 days, the abscess formation phase was observed on the 21st day, and the abscess recovery phase was observed on the 33rd day. Thus, the 21st day could be the optimal period for percutaneous transhepatic echo-guided intervention (Alvarez-Peréz et al, 2001;Balint et al, 2001;Alberti et al, 2002;Zatelli et al, 2005;Ferraioli et al, 2008;Meddings et al, 2010;Mezhir et al, 2010;O'Farrell et al, 2010;Angelino et al, 2011). To our knowledge, this is the first report of the establishment of a PHA animal model in the Bama minipig.…”