Clinical Correlates of Episodicity in Juvenile Mania

Abstract

These preliminary data indicate that, among children being treated for BPD in the community, those with discrete episodes of mania may be more likely to have a lifetime history of psychosis and a parental history of BPD. The latter hypothesis should be tested in a sample where relatives are interviewed directly.

History of suicide attempts in pediatric bipolar disorder: factors associated with increased risk

“…This prevalence rate is in the midrange of the three existing studies documenting suicide attempt rates in BP children and adolescents: 20% over 5-year follow up in BPI adolescents (10), 44% in a community sample of adolescents with BP spectrum disorders (11), and 15% for chronic BPI, 47% for episodic BPI pediatric patients (12). Differences in reported prevalence rates between these samples may be attributable to age ranges included in the sample (childhood versus adolescence), severity of the sample (BPI versus other BP types), time frame of suicide attempts assessed (lifetime versus follow up), and methods of assessing/defining suicide attempt employed in each of the studies.…”

“…In this sample, BP attempters (when compared with UP attempters) were younger at first attempt, made more lethal attempts, and were more likely to make multiple attempts. Bhangoo et al (12) reported a 47% attempt rate among BPI children and adolescents with an episodic pattern of mood symptomatology (one or more DSM-IV manic or hypomanic episodes), when compared with a 15% attempt rate for those patients with a chronic illness pattern (no discernable episodes).…”

Suicide risk factors in children and adolescents with bipolar disorder

“…Strober et al [ 8 ] reported a 20% rate of serious suicide attempts in a 5-year follow-up study of 54 bipolar adolescents. Bhangoo et al [ 9 ] reported a 27.6% rate of suicide attempts in a clinical sample of 87 bipolar patients aged 6 to 17 years. In an epidemiologic sample of 1709 adolescents, Lewinsohn et al [ 10 ] reported a 44.4% rate of suicide attempts in 18 adolescents with a bipolar spectrum disorder.…”

Transtorno de déficit de atenção/hiperatividade na infância e na adolescência: considerações clínicas e terapêuticas

“…A irritabilidade marcada associada a significativo descontrole de impulsos é a alteração de humor mais comum em crianças e adolescentes com THB, já que as mesmas tendem a não apresentar apenas humor eufórico como nos quadros clássicos do adulto (Leibenluft et al, 2003;Tramontina et al, 2003). A intensidade desses sintomas é significativamente maior nos quadros de THB na infância e na adolescência do que nos de TDAH, e existe uma episodicidade mais definida nos quadros de THB tipo I e II (não apenas sintomas pontuais) que muitas vezes não se consegue associar a qualquer mudança ambiental (Bhangoo et al, 2003). Assim, essas crianças têm episódios de dias (THB tipo II), ou de uma ou mais semanas (THB tipo I), em que uma flutuação do humor com valências mais extremas é facilmente notada.…”