Clinical correlates of difficult-to-treat depression: Exploring an integrated day-care model of treatment

Camardese, Giovanni; Mazza, Marianna; Zaninotto, Leonardo; Leone, Beniamino; Marano, Giuseppe; Serrani, Riccardo; Nicola, Marco Di; Bria, Pietro; Janiri, Luigi

doi:10.3109/08039488.2015.1048719

Cited by 4 publications

(3 citation statements)

References 50 publications

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“…Previous researchers have examined the effects of the numerous interventions specified in the model on the clients'/family caregivers' outcomes. These interventions include rehabilitation [18], physical activities [19], art programs [20], education or skills training [21], socialization [22], and family support and counseling [23]. Our model indicates that there are certain gaps in the research on inputs and interventions, which include "safe outdoor location", "opportunity for social contacts", "observing and evaluating clients' physical/psychiatric status", "ensuring food/water ingestion", and "providing bathing, cleansing, and grooming care".…”

Section: Discussionmentioning

confidence: 99%

A Logic Model for Evaluation and Planning in an Adult Day Care for Disabled Japanese Old People

Naruse

Kitano²,

Matsumoto

et al. 2020

IJERPH

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Adult day care (ADC) provides various services for meeting clients’ needs. Based on the mini-Delphi method with 46 ADC staff and the discussions with eight ADC administrators, this study developed and finalized a comprehensive logic model to represent the elements of ADC. For the three basic structures of a logic model—inputs/activities, outputs, and outcomes—the model contained seven core categories and 23 sub-categories. The ADC inputs/activities consisted of two core categories: “Place to stay” and “Intervention from staff”. These inputs/activities caused two kinds of outputs: “Clients’ experiences” and “Families’ experiences”. “Accumulating experiences” with repeated ADC visits was established as the link between the ADC outputs and outcomes, which were “Clients’ change” and “Families’ change”. ADC centers provide various experiences for their clients and their caregivers, ranging from the fulfillment of needs for fundamental care to psychiatric care and self-actualization. Improving various model-related inputs/interventions can produce better experiences and outcomes. The model can guide ADC administrators, policymakers, and researchers in the evaluation of a heterogeneous ADC service program that is community-based, thereby ensuring optimal care for clients with an efficient use of resources.

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Section: Discussionmentioning

confidence: 99%

A Logic Model for Evaluation and Planning in an Adult Day Care for Disabled Japanese Old People

Naruse

Kitano²,

Matsumoto

et al. 2020

IJERPH

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“… 70 Attainment of these goals should allow patients to travel along treatment and recovery journeys with greater ease and confidence, and to reach the desired destination of overall improved healthcare outcomes. 70 Additional advantages of adopting patient-centred care are the opportunities to engage patients’ families in care settings, 72 , 73 and to appropriately consider cultural traditions, family values, and socioeconomic factors, thereby potentially improving patient satisfaction and healthcare-professional productivity, and reducing the gamut of healthcare costs. 68 …”

Section: Potential Implications Of Electronic Enablers For Mdd Manage...mentioning

confidence: 99%

Improving Mental Health Outcomes in Patients with Major Depressive Disorder in the Gulf States: A Review of the Role of Electronic Enablers in Monitoring Residual Symptoms

Ahmed,

Reagu,

Alkhoori

et al. 2024

JMDH

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“…It is imperative to scrutinize all potential therapeutic avenues, particularly, when the achievement of symptomatic remission remains ambiguous. Family involvement is of paramount importance in the treatment of complicated and difficult depressions as evidenced by multiple academic surveys [ 10 , 13 ]. The dispositions of families and societal conceptions concerning DTD considerably influence the progression of the disorder [ 10 ].…”

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confidence: 99%

Viewpoint: Difficult-to-treat depression versus treatment-resistant depression: A new integrative perspective for managing depression

Paganin

2023

Eur. Psychiatr.

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In the STAR*D study, the efficacy of treatments for major depression was examined. It was found that, while many responded to the initial antidepressant treatment, only 30% of participants achieved complete remission. Concerning treatment resistance in depression, there is a recent distinction emerging between treatment-resistant depression (TRD) and difficult-to-treat depression (DTD). Historically, TRD and DTD have been conflated, but it is essential to recognize them as separate entities. While TRD is characterized by a patient's inadequate response to two or more consecutive antidepressant treatments given for an adequate duration and dosage without achieving acceptable therapeutic effects, DTD describes a clinical category where patients do not achieve full symptom control despite various therapeutic approaches. The recent shift in perspective proposes a more integrated approach for DTD, encompassing psychosocial, biological, and interactive factors. This multifactorial model calls for a multidisciplinary therapeutic intervention, not restricted to pharmacological treatments but also including psychotherapy, neurostimulation, and social interventions. Informing professionals and the general public about the significance of this new approach could mitigate the stigma associated with depression and enhance the quality of care. The future challenge will involve a deeper clinical understanding of DTD and its optimal management by refining available treatments.

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Clinical correlates of difficult-to-treat depression: Exploring an integrated day-care model of treatment

Abstract: Our intervention proved to be effective in the treatment of complex and severe forms of depression. Our results on the role of family support require further investigation to better define suitable targets for tailored therapeutic approaches.

Cited by 4 publications

References 50 publications

A Logic Model for Evaluation and Planning in an Adult Day Care for Disabled Japanese Old People

A Logic Model for Evaluation and Planning in an Adult Day Care for Disabled Japanese Old People

Improving Mental Health Outcomes in Patients with Major Depressive Disorder in the Gulf States: A Review of the Role of Electronic Enablers in Monitoring Residual Symptoms

Viewpoint: Difficult-to-treat depression versus treatment-resistant depression: A new integrative perspective for managing depression

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