Clinical characteristics, treatment, and outcome of pancreatic schwannomas

Paranjape, Charudutt; Johnson, Scott R.; Khwaja, Khalid; Goldman, Harvey; Kruskal, Jonathan B.; Hanto, Douglas W.

doi:10.1016/j.gassur.2004.05.010

Cited by 43 publications

(43 citation statements)

References 17 publications

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“…As the malignant transformation of pancreatic schwannomas is very rare, usually simple enucleation is usually suffice provided preoperative diagnosis confirmed with biopsy. [12] Otherwise, oncological resection in form of pancreaticoduodenectomy is indicated and recurrences are rare though close follow up is recommended.…”

Section: Discussionmentioning

confidence: 99%

Pancreatic Schwanoma Presenting as Gastric Outlet Obstruction- A Rare Presentation

Jayant¹,

Agrawal²,

Agarwal³

2014

AJCMR

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Introduction: Schwannoma is a very uncommon pancreatic neoplasms. Because of their varing size, cystic nature they mimic pancreatic cystic neoplasms. Mostly definitive diagnosis is confirmed with histological assessment post resection. The mainstay of treatment is surgical resection based on the nature of tumour. Case presentation: Here we are reporting a very rare case of pancreatic schwannoma in 45 year old female presenting with pain upper abdomen with projectile vomiting. Pre-operative diagnosis of heterogenous tumor arising from head of pancreas was made on CECT abdomen following which Whipple's procedure was performed. Post operative histological analysis showed spindle cells arranged in palisading pattern with S-100 positivity, confirms the diagnosis of pancreatic schwannoma. Conclusion: We conclude that pancreatic schwannoma must be considered as an important differential diagnosis of pancreatic neoplasms. Though they have non specific symptoms but can present in unusual way as gastric outlet obstruction. Pre-operative diagnosis is difficult though computed tomographic and magnetic resonance imaging may be of value. For benign tumors, simple enucleation is enough, while malignant tumors requires complete oncological resection.

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Section: Discussionmentioning

confidence: 99%

Pancreatic Schwanoma Presenting as Gastric Outlet Obstruction- A Rare Presentation

Jayant¹,

Agrawal²,

Agarwal³

2014

AJCMR

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“…Majority of these tumors located in the head (42.3%) and body (23%) of the pancreas [8]. Majority of tumors were benign (80.76%), but there were five reported malignancies (19.23%) [9]. Reported cases of intrapancreatic schwannoma have recently increased in the literature.…”

Section: Discussionmentioning

confidence: 99%

Pancreatic schwannoma: Report of a case and review of literature

Kinhal¹,

Ravishankar²,

Melapure³

et al. 2010

Indian J Surg

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Connective tissue tumors of pancreas are uncommon, among them pancreatic schwannoma is very rare tumor, very few cases were reported in literature. Aggressive resections like whipple's procedure, or distal pancreatectomy are not necessary for pancreatic schwannoma as it rarely goes to malignant change and simple enuclation is sufficient.In our patient pancreatic schwannoma is associated with simple cyst in liver and absence of one kidney. Here, we are presenting a case of pancreatic schwannoma treated by simple enucleation.

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“…Pancreatic schwannomas show no symptoms that are specifi c to the tumor, but the most common symptom was pain in the upper abdomen or right side of the abdomen, 6,8 which was found in 16 cases (48.5%; Table 1). Other symptoms including nausea, melena, body weight loss, and jaundice have also been noted.…”

Section: Discussionmentioning

confidence: 99%

“…Other symptoms including nausea, melena, body weight loss, and jaundice have also been noted. 6 An accurate preoperative diagnosis of pancreatic schwannomas is quite diffi cult, because they do not have any characteristic features that differ from those of other tumors on imaging studies such as EUS, CT, and MRI. 14,15 Unenhanced CT has shown the tumors to be well-defi ned, encapsulated, low-density cystic masses.…”

Section: Discussionmentioning

confidence: 99%

“…[2][3][4][5] We found, via a Medline search, only 27 reports of 32 cases of pancreatic schwannoma in the English-language literature. [6][7][8][9] An accurate preoperative diagnosis of this tumor is quite diffi cult if patients have neither any history nor fi ndings of von Recklinghausen disease. 7,10 Our present report describes a patient with pancreatic schwannoma, which was preoperatively diagnosed to be a mucinous cystic neoplasm (MCN) plus a literature review of this tumor.…”

Section: Introductionmentioning

confidence: 99%

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Pancreatic schwannoma: Report of a case

et al. 2008

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Among pancreatic neoplasms, pancreatic schwannoma is quite rare. We report a case of solitary pancreatic schwannoma, plus a literature review of this tumor. A 71-year-old woman was diagnosed by abdominal ultrasonography as having a pancreatic tumor and was hospitalized in our department at Kumamoto University Hospital on January 26, 2006. Abdominal computed tomography, magnetic resonance imaging, and endoscopic ultrasonography all showed this tumor, which was located in the body of the pancreas, to have cystic and solid components, and with a septum in the cystic part of the lesion. The tumor, preoperatively identified as a mucinous cystic neoplasm, was clearly separated from the normal pancreatic parenchyma. We performed a spleen-preserving distal pancreatectomy with a lymph node dissection on February 7, 2006. A histopathological examination of the resected specimen by means of hematoxylin and eosin revealed the tumor to consist of two parts: one with a compact spindle cell pattern (Antoni type A), and the other showing degeneration of fat (Antoni type B). We also found positive results for immunohistochemical staining for S-100 and vimentin. These findings confirmed the tumor's classification as a pancreatic schwannoma.

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Clinical characteristics, treatment, and outcome of pancreatic schwannomas

Cited by 43 publications

References 17 publications

Pancreatic Schwanoma Presenting as Gastric Outlet Obstruction- A Rare Presentation

Pancreatic Schwanoma Presenting as Gastric Outlet Obstruction- A Rare Presentation

Pancreatic schwannoma: Report of a case and review of literature

Pancreatic schwannoma: Report of a case

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