Clinical Cardiovascular Adverse Events Reported Post-COVID-19 Vaccination: Are They a Real Risk?

IgA vasculitis with transient glomerular hematuria, diarrhea, and pericarditis following COVID-19 mRNA vaccination in a young patient with possible pre-existing ulcerative colitis

“…The most common presentation after COVID-19 vaccine myocarditis or pericarditis is chest pain, followed by fever, and rarely headache, cough, and dyspnea [ 20 ]. Symptoms appear approximately 2–3 days after vaccination, most often after the second dose, and are associated with elevated troponin and CRP and an ECG with ST elevations in most reports [ 20 ]. Our patient did not have significant signs of myocardial injury, arrhythmia, or hemodynamic instability, refuting myocarditis.…”

“…Our patient did not have significant signs of myocardial injury, arrhythmia, or hemodynamic instability, refuting myocarditis. Most reported cases require hospitalization for up to 4 days but are still considered mild [ 20 ]. Our case also had a favorable clinical course.…”

“…Therefore, it is conceivable that the glomerular The most common presentation after COVID-19 vaccine myocarditis or pericarditis is chest pain, followed by fever, and rarely headache, cough, and dyspnea [20]. Symptoms appear approximately 2-3 days after vaccination, most often after the second dose, and are associated with elevated troponin and CRP and an ECG with ST elevations in most reports [20]. Our patient did not have significant signs of myocardial injury, arrhythmia, or hemodynamic instability, refuting myocarditis.…”

Clinical cardiovascular emergencies and the cellular basis of COVID-19 vaccination: from dream to reality?

“…COVID-19 vaccines especially in the adenoviral platform have been associated with the development of thrombotic thrombocytopenia ( Figure 1 ) ( Calcaterra et al, 2022 , Cines and Bussel, 2021 ). VAERS reported 5052 undefined thrombosis, 4144 pulmonary embolisms, 3001 deep veinous thromboses (DVT), 1195 thrombocytopenias and 233 cerebral venous sinus thromboses (CVST) among 604 million doses of SARS-CoV-2 vaccines in the United States ( Table 2 ) ( CDC, 2022 , Hana et al, 2022 ). In an independent study from Norway, Schultz and colleagues reported 5 cases of thrombotic thrombocytopenia among 130,000 individuals who were inoculated the AstraZeneca vaccine, and 4 of which were female ( Schultz et al, 2021 ).…”

Natural History of Myocardial Injury After COVID-19 Vaccine–Associated Myocarditis

“…As of March 1 st , 2022 more than 10 billion vaccine doses have been administered across 184 countries 1 . In this context, several case series [2][3][4][5][6][7][8][9][10] have reported rare occurrences of acute myocarditis early following vaccination, particularly among younger males [11][12][13] . These observations have led to expanding interest and concern regarding the downstream sequelae of this potentially serious complication.…”