Clinical Assessment of the Hyperbaric Oxygen Therapy Efficacy in Mild to Moderate Periodontal Affections: A Simple Randomised Trial

Abstract

Background and objectives: Gum disease represents the condition due to the dental plaque and dental calculus deposition on the surfaces of the teeth, followed by ulterior destruction of the periodontal tissues through the host reaction to the pathogenic microorganisms. The aim of study was to present aspects regarding the efficacy of hyperbaric oxygen therapy (HBOT) as an adjuvant therapy for the treatment of periodontal disease, started from the already certified benefits of HBOT in the general medicine specialties. Materials and methods: The participant patients in this study (71) required and benefited from specific periodontal disease treatments. All patients included in the trial benefited from the conventional therapy of full-mouth scaling and root planing (SRP) within 24 h. HBOT was performed on the patients of the first group (31), in 20 sessions, of one hour. The patients of the control group (40) did not benefit from HBO therapy. Results: At the end of study, the included patients in HBOT group presented significantly better values of oral health index (OHI-S), sulcus bleeding index (SBI), dental mobility (DM), and periodontal pocket depth (PD) than the patients of the control group. Conclusions: HBOT had beneficial effects on the oral and general health of all patients, because in addition to the positive results in periodontal therapy, some individual symptoms of the patients diminished or disappeared upon completion of this adjuvant therapy.

Oxygen-Releasing Hyaluronic Acid-Based Dispersion with Controlled Oxygen Delivery for Enhanced Periodontal Tissue Engineering

“…For the abovementioned reasons—in addition to its ability to inhibit the growth of anaerobic bacteria—hyperbaric oxygen therapy (HBOT) has been tested as adjuvant treatment of subgingival instrumentation for periodontitis, with promising results regarding the reduction of anaerobic bacteria and periodontal parameters [ 25 , 26 , 27 ]. Nevertheless, HBOT is a time-consuming and expensive procedure.…”

“…HA is a biological molecule found in different tissues of the human body. It occurs naturally in the gingiva, periodontal ligaments, dental cementum, and alveolar bone, and unstimulated saliva concentrations range from 148 to 1270 ng/mg [ 26 , 27 ]. Furthermore, HA is an important component of the extracellular matrix and plays an important role in cell migration and proliferation, contributing to wound healing and tissue regeneration [ 28 ].…”

An In Vitro Study of Local Oxygen Therapy as Adjunctive Antimicrobial Therapeutic Option for Patients with Periodontitis

“…In a clinical study by Burcea et al [ 19 ] patients in the HBOT group had significantly better oral health index (OHI-S), sulcus bleeding index (SBI), dental mobility, and periodontal probing depth scores than patients in the control group (subgingival instrumentation only). In a study by Chen et al [ 20 ] HBOT inhibited the growth of subgingival obligate anaerobes and facultative anaerobes as well as Bacteroides melaninogenicus , thus promoting periodontal healing.…”

Comparative oral health outcomes before and after periodontitis treatment: Scaling and root planning alone versus Nd: YAG Laser Assisted New Attachment Procedure.

“…For these, it is necessary to thoroughly acknowledge disease characteristics and personalized therapies [10]. This goal can be achieved by removing plaque, subgingival calculus and the biofilm layer to obtain a clean and polished dental surface with no retention of dental plaque and calculus [11,12].…”