Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia

Saad, Mustafa; Omrani, Ali S.; Baig, Kamran; Bahloul, Abdelkarim; Elzein, Fatehi; Matin, Mohammad A.; Selim, Mohei A.; Mutairi, Mohammed Al; Nakhli, Daifullah Al; Aidaroos, Amal Y. Al; Sherbeeni, Nisreen Al; Al-Khashan, Hesham I.; Memish, Ziad A.; Albarrak, Ali

doi:10.1016/j.ijid.2014.09.003

Cited by 454 publications

(536 citation statements)

References 20 publications

(30 reference statements)

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“…This study describes the largest sample of confirmed MERS-CoV cases and confirms previous study findings indicating males are predominately affected by this disease [6,7] and is in comparison to Severe Acute Respiratory Syndrome (SARS), where there is a predominance of females in all cases [8]. Healthcare workers were at high risk and accounted for one-sixth of all cases, in comparison to SARS in which healthcare workers accounted for one-fifth of all cases.…”

Section: Discussionsupporting

confidence: 86%

Middle East Respiratory Syndrome: Global Outbreak Data Analysis

Alsolamy¹,

Yousif²,

Alotabi³

et al. 2017

J Infect Dis Preve Med

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Section: Discussionsupporting

confidence: 86%

Middle East Respiratory Syndrome: Global Outbreak Data Analysis

Alsolamy¹,

Yousif²,

Alotabi³

et al. 2017

J Infect Dis Preve Med

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“…In one observational study at a single center in Saudi [19]. Severe neurologic syndrome, including altered level of consciousness, ranging from confusion to coma, ataxia, and focal motor deficit, has been reported in three critically ill MERS-CoV patients, with brain magnetic resonance imaging (MRI) showing widespread, bilateral hyperintense lesions on T2-weighted images in the white matter and subcortical areas of different brain areas [27].…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Critically Ill Patients with Middle East Respiratory Syndrome Coronavirus Infection

Al‐Dorzi

Alsolamy

Arabi

2016

Annual Update in Intensive Care and Emergency Medicine

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“…[4,5,6] Human-tohuman transmission of MERS-CoV is all around recorded in the family, group settings and more frequently in social insurance settings [4,7,8]. As such, bigger hospital outbreaks have been driven by a combination of overdue recognition, over-crowding, and inadequate infection control precautionary measures [6,9,10]. In any case, MERS-CoV between human transmissibility is believed to be moderately restricted.…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Perception of Health Practitioners towards MERS-CoV in Hail Region, Kingdom of Saudi Arabia

Alshammari¹

2018

AJNR

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Objective: This research determines the level of knowledge and the perceptions of the health practitioners about MERS-CoV to target the needs in addressing the health threat. It also aims to relate the participants' age, gender, civil status and educational attainment between the seriousness, susceptibility and extent of anxiety, efficacy, and self-efficacy, and the intention to carry out the measures. Methods: This research utilized a correlational approach. The participants were the health practitioners in the hospitals of Hail Region, Kingdom of Saudi Arabia. A total of 264 health practitioners completed the survey (response rate of 83%) as a result of a convenience sampling. Weighted mean, standard deviation and Chi-square test of independence were used to analyze the data. Results: The health practitioners have high knowledge on MERS-CoV; as an inflammation of the lungs (2.64 ± 0.48); always gives symptoms (2.67± 0.52), and can be prevented by practicing good hygiene (2.62 ±0.64). The MERS-CoV is perceived as a very serious disease (4.24±0.56). Moreover, the susceptibility of MERS-CoV, and extent of anxiety are perceivably contracted in the absence of preventive measures (3.30±1.18), and with no vaccination (2.7±0.90). On efficacy/self-efficacy, the health practitioners are very certain (4.40 ± 0.69) and neutral with their intention to carry out the measures (3.38±0.72). Age (P=0.001), civil status (P=0.026) and educational attainment (P=0.001) yielded significant relationship with the intention to carry-out the measures. Equally, the educational attainment (P=0.031) prove significant to efficacy and self-efficacy. Conclusion: The high level of knowledge and good perception of the health practitioners about MERS-CoV may contribute in anticipating the disease outbreak.

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Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia

Abstract: MERS-CoV can cause severe infection requiring intensive care and has a high mortality. Concomitant infections and low albumin were found to be predictors of severe infection, while age ≥65 years was the only predictor of increased mortality.

Cited by 454 publications

References 20 publications

Middle East Respiratory Syndrome: Global Outbreak Data Analysis

Middle East Respiratory Syndrome: Global Outbreak Data Analysis

Critically Ill Patients with Middle East Respiratory Syndrome Coronavirus Infection

Knowledge and Perception of Health Practitioners towards MERS-CoV in Hail Region, Kingdom of Saudi Arabia

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