Clinical Application of Ultrasound Imaging in Radiation Therapy

Kim, Hayeon; Brandner, E; Huq, M. Saiful; Beriwal, Sushil

doi:10.5772/19245

Cited by 2 publications

(2 citation statements)

References 40 publications

(45 reference statements)

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“…For gynecological applications (endometrial or cervical cancer) target definition is generally complex due to the presence of multiple structures, which move and deform significantly during treatment. US images typically cannot show the entire target but, if the bladder is full, uterus, cervix and vagina can be correctly visualized (Kim et al 2011).…”

Section: Target Volume Delineationmentioning

confidence: 99%

Review of ultrasound image guidance in external beam radiotherapy: I. Treatment planning and inter-fraction motion management

et al. 2015

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In modern radiotherapy, verification of the treatment to ensure the target receives the prescribed dose and normal tissues are optimally spared has become essential. Several forms of image guidance are available for this purpose. The most commonly used forms of image guidance are based on kilovolt or megavolt x-ray imaging. Image guidance can also be performed with non-harmful ultrasound (US) waves. This increasingly used technique has the potential to offer both anatomical and functional information.This review presents an overview of the historical and current use of two-dimensional and three-dimensional US imaging for treatment verification in radiotherapy. The US technology and the implementation in the radiotherapy workflow are described. The use of US guidance in the treatment planning process is discussed. The role of US technology in inter-fraction motion monitoring and management is explained, and clinical studies of applications in areas such as the pelvis, abdomen and breast are reviewed. A companion review paper (O'Shea et al 2015 Phys. Med. Biol. submitted) will extensively discuss the use of US imaging for intra-fraction motion quantification and novel applications of US technology to RT.

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Section: Target Volume Delineationmentioning

confidence: 99%

Review of ultrasound image guidance in external beam radiotherapy: I. Treatment planning and inter-fraction motion management

et al. 2015

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“…Ultrasound (US) imaging is an important technique for soft tissues, used both for diagnostic (Brascho 1977) and verification purposes (Kim et al 2011) in radiotherapy. The advantages of this modality are high resolution, acquisition speed, reliability, absence of side effects, cost and maintenance efficiency, and exciting novel developments (Freeman 2011).…”

Section: Introductionmentioning

confidence: 99%

A speed of sound aberration correction algorithm for curvilinear ultrasound transducers in ultrasound-based image-guided radiotherapy

Fontanarosa¹,

Pesente²,

Pascoli³

et al. 2013

Phys. Med. Biol.

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Conventional ultrasound (US) devices use the time of flight (TOF) of reflected US pulses to calculate distances inside the scanned tissues and thus create images. The speed of sound (SOS) is assumed to be constant in all human soft tissues at a generally accepted average value of 1540 m s(-1). This assumption is a source of systematic errors up to several millimeters and of image distortion in quantitative US imaging. In this work, an extension of a method recently published by Fontanarosa et al (2011 Med. Phys. 38 2665-73) is presented: the aim is to correct SOS aberrations in three-dimensional (3D) US images in those cases where a spatially co-registered computerized tomography (CT) scan is also available; the algorithm is then applicable to a more general case where the lines of view (LOV) of the US device are not necessarily parallel and coplanar, thus allowing correction also for US transducers other than linear. The algorithm was applied on a multi-modality pelvic US phantom, scanned through three different liquid layers on top of the phantom with different SOS values; the results show that the correction restores a better match between the CT and the US images, reducing the differences to sub-millimeter agreement. Fifteen clinical cases of prostate cancer patients were also investigated: the SOS corrections of prostate centroids were on average +3.1 mm (max + 4.9 mm-min + 1.3 mm). This is in excellent agreement with reports in the literature on differences between measured prostate positions by US and other techniques, where often the discrepancy was attributed to other causes.

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Clinical Application of Ultrasound Imaging in Radiation Therapy

Cited by 2 publications

References 40 publications

Review of ultrasound image guidance in external beam radiotherapy: I. Treatment planning and inter-fraction motion management

Review of ultrasound image guidance in external beam radiotherapy: I. Treatment planning and inter-fraction motion management

A speed of sound aberration correction algorithm for curvilinear ultrasound transducers in ultrasound-based image-guided radiotherapy

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