Clinical Application of Platelet-Rich Fibrin by the Application of the Double J Technique During Implant Placement in Alveolar Bone Defect Areas

Kim, Jin-Son; Jeong, Moon-Hwan; Jo, Ji-Ho; Kim, Su-Gwan; Oh, Jaewon

doi:10.1097/id.0b013e3182920da3

Cited by 5 publications

(3 citation statements)

References 20 publications

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“…The three‐dimensional fibrin architecture of PRF provides a microenvironment conducive to cell migration, proliferation, differentiation, and adhesion to promote osteogenesis 27 . PRF matrix also functions as a bioactive interface between soft tissues and bone compartment avoiding the migration of soft tissues in bony defect, a biological characteristic termed as “competitive barrier” to favor bone regeneration 28 . In addition, PRF promotes soft tissue healing through neo‐vascularization and gradual release of growth factors.…”

Section: Discussionmentioning

confidence: 99%

“…27 PRF matrix also functions as a bioactive interface between soft tissues and bone compartment avoiding the migration of soft tissues in bony defect, a biological characteristic termed as "competitive barrier" to favor bone regeneration. 28 In addition, PRF promotes soft tissue healing through neovascularization and gradual release of growth factors. It stimulates the healing of a damaged flap and reduces the risk of flap necrosis unlike GTR membranes.…”

Section: Case Reportmentioning

confidence: 99%

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Successful management of a large mucosal fenestration at 18‐months follow‐up

Yadav

Gupta

Chawla

et al. 2021

J Esthet Restor Dent

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Objectives Mucosal fenestrations are infrequent and often challenging to treat depending on the extent of soft and hard tissue destruction. This article presents the successful management of a relatively larger mucosal fenestration associated with complete absence of buccal bone plate in a mandibular incisor secondary to trauma‐induced periapical pathosis. Clinical considerations After non‐surgical endodontic therapy, surgery was performed for debridement of the osseous defect, root resection/shaping, connective tissue graft (CTG) placement on the affected root surface and platelet rich fibrin (PRF) in periapical osseous defect rather than use of bone graft and/or barrier membrane. Healing was uneventful, however, a small mucosal defect remained at 2 weeks follow‐up. After 3 months of primary surgery, a corrective surgery was performed utilizing an “incision‐free” approach i.e. tunnel technique with CTG in contrast to the contemporary flap approach. At 18 months follow‐up, complete closure of the mucosal defect with a thick gingival biotype, normal sulcus depth, and good esthetic outcome were achieved. No recurrence and any clinical signs of infection or inflammation were observed. Conclusions Based on the outcomes of present case, an early intervention utilizing the minimally invasive surgical therapy and autologous biomaterials may be considered a viable approach to treat such complex lesions. Clinical significance Endodontic therapy in combination with PRF and CTG appears to provide successful outcomes in treatment of a large mucosal fenestration with periapical osseous defect.

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Section: Discussionmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Successful management of a large mucosal fenestration at 18‐months follow‐up

Yadav

Gupta

Chawla

et al. 2021

J Esthet Restor Dent

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“…If the patient's blood is centrifuged in a sterilized plastic vacuum tube not containing silica, two layers are formed with the red blood cells at the bottom layer and plasma layer on top. Mixing acellular plasma with bone graft materials agglutinates the material, making it easier for the surgeon to place the graft materials on the defect area[26].…”

mentioning

confidence: 99%

Guided bone regeneration in peri-implant defects using a 1:1 mixture of cancellous and cortical freeze-dried bone allograft: A randomized controlled trial

et al. 2019

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The results of guided bone regeneration (GBR) in peri-implant defects using anorganic bovine bone (ABB) were compared with those using a 1:1 mixture of cancellous and cortical freeze-dried bone allograft (FDBA). In total, 37 participants (10 males and 27 females) and 63 sites were evaluated. Full mucoperiosteal flap was reflected followed by implant insertion. The length and width of the defect were measured using a periodontal probe. Furthermore, the most buccal (D is) and lingual (D d) points of the exposed implant surface at the implant shoulder level were determined. The participants were randomly divided into two groups based on the graft material used: ABB only (control group) and 1:1 mixture of cancellous and cortical FDBA allograft (experimental group). Each transplanted site was covered by the collagen barrier membrane. After 5-6 months of surgery, re-entry was performed, and any residual defect length and width were measured. Moreover, the amount of regenerated bone was measured by calculating the distance from the D is and D d points to the regenerated bone in the buccolingual direction. Between-group comparisons were performed using the t-test. No differences in defect length, exposed implant surface, and horizontal bone gain were observed between ABB and allograft. Similarly, no significant differences in these measures and the defect width were observed between the two materials in both the maxilla and mandible. The 1:1 mixture of cancellous and cortical FDBA allograft combined with resorbable barrier membrane could be an effective alternative for ABB for the treatment of peri-implant defects when using GBR.

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