Clinical and Radiographic Evaluation of Aloe vera vs Formocresol as a Pulpotomy Medicament in Primary Molars: A Double Blinded Randomized Controlled Trial

Abstract

Aim The aim of this clinical trial is to compare the clinical and radiographic success of Aloe vera and formocresol (FC) as a pulpotomy medicament in primary molars. Materials and methods A total of 72 asymptomatic or symptomatic vital primary molars were selected and were assigned to two groups: group II: Buckley's FC, group II: Aloe vera gel. The clinical and radiographic success were evaluated using Zurn and Seale criteria. The data were statistically analyzed using the Chi-square test. Results At three and 6 months follow-up, the clinical success rate of Aloe vera and FC was equally effective. Aloe vera showed a higher radiographic success rate compared to FC ( p > 0.05). At 6 months follow-up, FC showed a higher radiographic success rate compared to Aloe vera ( p > 0.05). Conclusion The clinical and radiographic success of both groups were equally effective at the end of 6 months follow-up. Aloe vera can be considered as an alternative pulpotomy medicament to FC. But, further long-term follow-up studies and histological studies are required. How to cite this article Subramanyam D, Somasundaram S. Clinical and Radiographic Evaluation of Aloe vera vs Formocresol as a Pulpotomy Medicament in Primary Molars: A Double Blinded Randomized Controlled Trial. Int J Clin Pediatr Dent 2020;13(2):138–143.

Regenerative potential of a novel aloe vera modified tricalcium silicate cement as a pulp capping material: An animal study

“…This agrees with the results of Alharbi et al 31) At 2 weeks intervals, the exposed pulpal area of samples treated with 20% and 30% AV-modified Matreva MTA was partially covered with calcified tissue (50% and 66.7%, respectively). This agrees with a previous study 32) that demonstrated AV's radiographic and clinical success as a pulpotomy or as a direct pulp capping material. Moreover, in animal models, AV's histological findings revealed stem cell differentiation and organization, the proliferation of pulp cells as well as dentine formation, and mineralization 29,33) .…”