2021
|
|

Abstract: Background. Periodontal disease is one of the major causes of alveolar bone loss. There are various ways of regenerating the lost bone, i.e. guided tissue regeneration, bone grafts, and growth factors. In this purview, it becomes immensely important for a clinician to decide the best modality of treatment. In this study, we compared the effect of demineralized freeze-dried bone allograft (DFDBA) in combination with concentrated growth factors (CGF) verses CGF alone. Methods. This double-blind, split-mout… Show more

Help me understand this report

Search citation statements

Order By: Relevance
Select...
2
1
1
2
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
3

Relationship

1
2

Authors

Journals

1
2
0
Order By: Relevance
“…Similarly, the pocket probing depth at sites treated with DFDBA also showed a significant decrease at the end of six months. The current study results align with earlier studies [42][43][44][45][46]. But the sites treated with DFDBA showed a better improvement when compared to the sites treated with BCP.…”
Section: Discussionsupporting
“…BMP can mediate osteogenesis alone and promote the formation of bone matrix and form calcified bone tissue when mix with other bone growth factors. TGF-β, as an important regulatory factor in the process of bone formation and remodeling, controls inflammation through synthetic fibrous connective tissue and local vascular proliferation, and also induces regeneration of alveolar bone [ 33 ].…”
Section: Discussionmentioning
“…CGF is mainly composed of concentrated platelets, white blood cells, cytokines, and fibrin with a reticular structure, and is prepared with relation to the coagulation of blood. CGF contains TGF-1, platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and insulin-like growth factor-1 (IGF-1), among others (Keranmu et al, 2021;Vaid et al, 2021). The scaffold network structure of CGF slows the release of the growth factors.…”
Section: Concentrated Growth Factorsmentioning