Clinical and metabolic features of polycystic ovary syndrome

Li, Lin; Yang, Dongzi; Chen, Xiaoli; Chen, Yaxiao; Shen, Feng; Wang, Liangan

doi:10.1016/j.ijgo.2007.01.005

Cited by 60 publications

(42 citation statements)

References 31 publications

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“…Another factor, which contributed to the lower prevalence of MetS in our population of PCOS patients, was BMI. The BMI values in the Chinese PCOS patients were usually lower and central obesity less popular than other ethnicities (30,(33)(34)(35), whereas central obesity is one of the main contributors to developing the MetS. In our study, mean BMI was also lower than those in America, Germany, Australia, India, and Thailand.…”

Section: Discussioncontrasting

confidence: 42%

Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome

Ni¹,

Mo²,

Chen³

et al. 2009

European Journal of Endocrinology

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Objective: Variations in the prevalence of metabolic syndrome (MetS) among women with polycystic ovary syndrome (PCOS) in different races were reported. We sought to report this prevalence and its components in Chinese women with PCOS and compared these characteristics with healthy controls. Design: Anthropometric measurements and biochemical parameters were evaluated in 578 PCOS patients diagnosed by the Rotterdam criteria and 281 age-and body mass index (BMI)-matched controls. International Diabetes Federation criteria for MetS were used. Results: The prevalence of MetS was 16.8% in this study, and 60.7% of patients displayed at least one component of MetS. Among the patients, the rates of dyslipidemia, impaired fasting glucose, and elevated blood pressure were 41.6, 19.8, and 16.1% respectively; the rates of these corresponding components in age-and BMI-matched controls were 14.6, 5.3, and 5.7% respectively. In PCOS patients, the prevalence of MetS was 0.0, 3.9, 20.2, and 51.1% for four different BMI groups respectively; the prevalence of MetS was 7.3, 14.9, 24.2, and 42.4% in the four age groups respectively. Nearly 90% of patients diagnosed with MetS belonged to overweight and obese groups. BMI and age rather than free testosterone, free androgen index, fasting insulin, or sex hormone-binding globulin were included in formulation for predicting MetS according to multivariable logistic regression. Conclusions: Low prevalence of MetS but high occurrence of various metabolic disorders was found in women with PCOS compared with age-and BMI-matched controls in this study. BMI and age appeared to contribute more to developing MetS than other parameters associated with insulin resistance or hyperandrogenism.

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Section: Discussioncontrasting

confidence: 42%

Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome

Ni¹,

Mo²,

Chen³

et al. 2009

European Journal of Endocrinology

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“…Menstrual irregularity was observed in 83% of our patients while study conducted by Vrunda Dhagat reported 65% in the same [9]. The frequency of hirsutism was comparable to that noted in Chinese women (35%), while acne was present only in 13% patients, as compared to 45% in the Chinese study group [10]. Apparently, 57% of the married patients were fertile even though only 25% reported worldwide [11].…”

Section: Discussionsupporting

confidence: 56%

Clinical Profile of Patients with Polycystic Ovarian Syndrome in Nepal

Joshi¹

2017

EMIJ

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Background: Polycystic Ovarian Syndrome is a common gynecological endocrinopathy characterized by chronic an ovulation and hyperandrogenism. The disorder is heterogeneous and is one of the most common treatable causes of infertility.Objectives: To evaluate the clinical, biochemical and hormonal profile of patients with PCOS in Nepalese patients.Methodology: A retrospective analysis of the clinical data and hormonal profile of patients with Polycystic Ovary Syndrome at Kathmandu Diabetes and Thyroid Center Pvt Ltd, Lalitpur, Nepal was undertaken. Results:The mean age of 80 patients in this study group was 24 ± 6 years. Menstrual irregularity was the most common presenting problem occurring in 83% patients, followed by infertility (43%) and hirsutism (33%). Hyperandrogenism was demonstrated in 82%. USG feature of Polycystic Ovarian Syndrome was apparent in 60% patients. The mean Body Mass Index was 27.4 ± 5.1 kg/m2. Diabetes, hypertension and hypothyroidism were noted among 2%, 4% and 30% of the patients respectively. Conclusion:Our study concluded that menstrual irregularity was the most common presenting problem of Polycystic Ovarian Syndrome in our patient population. The condition is treatable and should be considered in patients presenting with infertility.

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“…Its prevalence ranges from 4%-12% in general population of women in the world of reproductive age. [22][23][24][25][26][27][28] Although there are no systemic studies from India, the observations by endocrinologists, gynaecologists, dermatologists, etc. show a significant rise in number of females with PCOS nevertheless prevalence of PCOS in Indian adolescents estimated at 9.13%.…”

Section: Introductionmentioning

confidence: 99%