Clinical Profile of Patients with Polycystic Ovarian Syndrome in Nepal

Abstract

Background: Polycystic Ovarian Syndrome is a common gynecological endocrinopathy characterized by chronic an ovulation and hyperandrogenism. The disorder is heterogeneous and is one of the most common treatable causes of infertility.Objectives: To evaluate the clinical, biochemical and hormonal profile of patients with PCOS in Nepalese patients.Methodology: A retrospective analysis of the clinical data and hormonal profile of patients with Polycystic Ovary Syndrome at Kathmandu Diabetes and Thyroid Center Pvt Ltd, Lalitpur, Nepal was undertaken. Results:The mean age of 80 patients in this study group was 24 ± 6 years. Menstrual irregularity was the most common presenting problem occurring in 83% patients, followed by infertility (43%) and hirsutism (33%). Hyperandrogenism was demonstrated in 82%. USG feature of Polycystic Ovarian Syndrome was apparent in 60% patients. The mean Body Mass Index was 27.4 ± 5.1 kg/m2. Diabetes, hypertension and hypothyroidism were noted among 2%, 4% and 30% of the patients respectively. Conclusion:Our study concluded that menstrual irregularity was the most common presenting problem of Polycystic Ovarian Syndrome in our patient population. The condition is treatable and should be considered in patients presenting with infertility.