Clinical and Histopathological Study on Dog's Tumors in Iraq

Abstract

The study was conducted on twenty dogs from variety breeds to estimate the incidence of tumor mass and determine the risk factors of survey to cases of a year in veterinary hospital in Baghdad. The most common clinical signs were, ulceration, bleeding into lesions in addition to drowsiness, anorexia, fever and the others were depended tumor's location in dog's body like lameness, lacrimation and bloody constipation etc.The results showed 70% of the infected dogs were working with military forces and 30% of them were pet dogs and we found that the highest percentage of tumor accrued in dogs aged more than 10 years and the females recorded 60% of infection.Terrier breed had the highest percentage of infection (30%) followed by German shepherd (25%). the most tumor affected part of the body were mammary glands in females and the limbs in both gender (25% each one) and followed by the other sites, the histopathology picture had recorded seven types of malignant tumors in (skin, intestine and mammary glands) more frequent was Sequmas cell carcinoma 35% Adenocarcinoma 20%. Some dogs had more than one type of cancer, and some cases had recorded of benign tumors other cases had only transformed tissue but not cancer. Keywords ISSN: 0067-2904Alabbody et al. Science, 2017, Vol. 58, No.3C, pp: 1617 Iraqi Journal of IntroductionCancers in dogs occur naturally, so it is one of the best cancer model for human and cancer studies, because these tumor are various, infect the aged and obese, otherwise dogs live in the same environment so exposed to same carcinogens. Dogs are greater resembling humans biologically, such as (telomere and telomerase actions) in addition to common spontaneous epithelial cancer [1, 2], many anatomic and clinical resemble are seamed such as type and subtypes of cancer between the two species, and same treatment schemes [3].Cancer is the chief cause of death in dogs over 10 years in aged , with 50% of older dogs developing the disease and approximately one in four dogs eventually dying from it. [4] The primary studies to natural dog tumors could be for developing the knowledge about human cancers [5]. All breeds, both sex and all ages are able to infect with cancer but there are variables. Multiple cancers are common to find in some breeds, in other side, there is specific cancer for specific breed. Histiocytic cancer covers a broad range of clinical appearances, from benign cutaneous histiocytoma to highly aggressive histiocytic sarcoma (HS). HS is a multisystem disease with tumors appearing at the same time like the skin or subcutis, or other organs. This is a virulent and fatal disorder of dendritic cell origin [6].Cancer incidence of dogs is rising. Invert of other animals, the good health care of pets lead to early correct diagnosis of cancer, more cure because owners are ready to pay for diagnostic tests and treatment. Veterinary epidemiologists get better their ability to track canine cancer. Scientists are more work to know which breeds are at an increased risk of each type of cancer. ...

Pathological study of neoplasms surgically excised from animals attended the veterinary teaching hospital

“…The most common types of tumour that have been recorded in Iraq are cutaneous papilloma, cutaneous fibroma, hepatic adenoma, cutaneous squamous cell carcinoma, lipoma, and thymoma (2)(3)(4)(5). Few of previous studies explained the histological nature of these types of tumours; others were describing the gross lesions with emphasizing on the clinical aspects of these cases (7). In Mosul city, the neoplastic masses which have been recorded are bovine cutaneous papilloma, cutaneous squamous cell carcinoma, and mixed thymic tumour (2,3,5).…”