Clinical and Histopathologic Characteristics of Skin Malignancies in Qassim Region , Saudi Arabia

Alzolibani, Abdullateef A.; Shobaili, Hani A. Al; Robaee, Ahmad A. Al; Khan, Athar Ali; Haque, Imran Ul; Rao, Nagendra Seethapathi; Alrejaie, Abdulaziz

doi:10.12816/0006021

Cited by 12 publications

(18 citation statements)

References 15 publications

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“…Table summarizes the incidence of skin cancer in several geographic areas in Saudi Arabia. The head and neck was the commonest location of both cancers in our center and in all skin cancer studies published in Saudi Arabia …”

Section: Discussionmentioning

confidence: 80%

“…The reason of this racial difference is unknown . It is the third most common cutaneous malignancy at our center and is the fourth most common malignancy in most regions of Saudi Arabia …”

Section: Discussionmentioning

confidence: 98%

“…The lower extremities were the commonest location of malignant melanoma. Of note, all previous studies published in Saudi Arabia included Saudis and non‐Saudis, with non‐Saudis being less than 5% of all patients included …”

Section: Discussionmentioning

confidence: 99%

“…The head and neck was the commonest location of both cancers in our center and in all skin cancer studies published in Saudi Arabia. [14][15][16][17][18][19][20] Malignant melanoma is the third most common cutaneous malignancy among Asians, Hispanics, black people, and Caucasians. [1][2][3][4][5]9,10,21 It is the fifth leading cancer in American men and the seventh leading cancer in American women.…”

Section: Discussionmentioning

confidence: 99%

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Pattern of skin cancer among Saudi patients attending a tertiary care center in Dhahran, Eastern Province of Saudi Arabia. A 20‐year retrospective study

Al-Dawsari

Amra

2016

Int J Dermatology

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Skin cancer is the ninth most common malignancy in Saudi Arabia. It represented 3.2% of all newly diagnosed cancer cases in the year 2010. The aim of this study was to determine the epidemiology of skin cancer in relation to age, sex, and anatomic location among Saudi patients attending the Johns Hopkins Aramco Healthcare center in Dhahran, Eastern province of Saudi Arabia. We retrospectively reviewed the surgical pathology records of Saudi nationals from 1995 to 2014 at the Johns Hopkins Aramco Healthcare center, which directly provides for the healthcare needs of Saudi Aramco company employees and dependents in the Eastern Province of Saudi Arabia. Tumor metastases to skin, skin involvement by primary breast carcinoma, and B-cell leukemia/lymphoma with secondary involvement by skin were excluded. The total number of primary skin tumors was 204. The commonest cutaneous malignancies were basal cell carcinoma (36%) followed by squamous cell carcinoma (23%), with the head and neck being the commonest location for both tumors. Mycosis fungoides (MF) was the third most common malignancy (11%). Malignant melanoma was the fourth commonest skin malignancy (7%) with the lower extremities being the commonest location. The four most common skin cancers in our tertiary center in the Eastern Province of Saudi Arabia were squamous cell carcinoma, basal cell carcinoma, MF, and malignant melanoma. Other regions of Saudi Arabia report a similar pattern of skin cancers as our center, with MF having a higher frequency at our center.

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Section: Discussionmentioning

confidence: 80%

“…The reason of this racial difference is unknown . It is the third most common cutaneous malignancy at our center and is the fourth most common malignancy in most regions of Saudi Arabia …”

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Pattern of skin cancer among Saudi patients attending a tertiary care center in Dhahran, Eastern Province of Saudi Arabia. A 20‐year retrospective study

Al-Dawsari

Amra

2016

Int J Dermatology

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“…Notably, during the study period, the incidence of CSCC decreased in females and increased in males (5). Although there are no population-based incidence studies in Saudi Arabia, CSCC is the second most common type of skin cancer after basal cell carcinoma (BCC) with an estimated incidence of 18% (17 out of 94) to 42% (57 out of 137) of all skin cancers (6)(7)(8).…”

Section: Incidencementioning

confidence: 99%

A Review of Cutaneous Squamous Cell Carcinoma Epidemiology, Diagnosis, and Management

2018

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Introduction: Cutaneous squamous cell carcinoma (CSCC) is the second most common type of skin cancer and its incidence continues to rise worldwide. While the majority of CSCCs have excellent prognosis, a subset have the propensity to cause poor outcomes. Evidence Acquisition: A thorough Pubmed search was done and a collection of CSCC-relevant articles were selected based on the expert opinion. Results: A number of high-risk factors have been identified including perineural invasion (PNI), desmoplastic growth pattern, poor differentiation, high risk location and large diameter. Various staging systems have been developed based on these high-risk factors. Radiologic imaging is important for high-stage tumors and is likely associated with more aggressive management. Conclusions: Although surgical management is the gold standard, newer therapies such as programmed cell death protein-1 (PD-1) inhibitors show promise for locally advanced or metastatic disease. Despite advances in treatment, early diagnosis and prevention of CSCC is still the most important measure to ensure good outcomes.

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A retrospective study of malignant melanoma from a tertiary care centre in Saudi Arabia from 2004 to 2016

et al. 2019

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Clinical and Histopathologic Characteristics of Skin Malignancies in Qassim Region , Saudi Arabia

Abstract: Abstract:Background and objective: The present study was undertaken to assess the pattern of skin malignancies in Qassim region, Kingdom of Saudi Arabia.

Cited by 12 publications

References 15 publications

Pattern of skin cancer among Saudi patients attending a tertiary care center in Dhahran, Eastern Province of Saudi Arabia. A 20‐year retrospective study

Pattern of skin cancer among Saudi patients attending a tertiary care center in Dhahran, Eastern Province of Saudi Arabia. A 20‐year retrospective study

A Review of Cutaneous Squamous Cell Carcinoma Epidemiology, Diagnosis, and Management

A retrospective study of malignant melanoma from a tertiary care centre in Saudi Arabia from 2004 to 2016

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