The work investigates risk factors (RFs) and associated conditions (ACs) by gender in patients with stage III arterial hypertension (HTN). RFs and ACs were compared in men (45, average age 63.58 ± 9.12) and women (53, age 65.19 ± 10.02) with verified HTN. Age correlation of the parameters was carried out. In women, compared to men, HTN is diagnosed earlier, with longer disease duration (DD). Obesity (O), increased body mass index (BMI), left ventricular hypertrophy (LVH), decreased glomerular filtration rate (GFR) are more common. Women more often have acute cerebrovascular accidents (ACVAs) and transient ischemic attacks (TIAs), diabetes mellitus (DM). Men have a higher percentage of smokers, higher pulse pressure, damaged peripheral arteries. At the same time, ischemic heart disease (IHD) and heart failure (HF) are equally common. There is a multidirectional correlation between age and disease duration (DD), weight, lipid profile and blood glucose (BG) levels in both men and women. Men and women have differences in the presence and severity of RFs, ACs and correlation between age and the studied parameters.