Clinical and Experimental Aspects of Barbiturate Withdrawal Convulsions

Essig, Carl F.

doi:10.1111/j.1528-1157.1967.tb03816.x

Cited by 46 publications

(2 citation statements)

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“…It is generally accepted that relatively rapid AED withdrawal leads to a higher chance of recording the patient's seizures. Clinicians should be aware of the heightened risk of withdrawal seizures resulting from the rapid withdrawal of barbiturates and benzodiazepines even in persons without epilepsy. AED withdrawal does not affect the EEG pattern of seizure onset, even when associated with increased seizure frequency, secondary generalization, and clustering …”

Section: Anticipated Course Of Treatment In Emu For Medical and Presumentioning

confidence: 99%

Indications and methodology for video‐electroencephalographic studies in the epilepsy monitoring unit

et al. 2017

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SummaryAlthough the epilepsy and neurology communities have position papers on a number of topics pertaining to epilepsy diagnosis and management, no current paper exists for the rationale and appropriate indications for epilepsy monitoring unit (EMU) evaluation. General neurologists, hospital administrators, and insurers also have yet to fully understand the role this type of testing has in the diagnosis and management of individuals with paroxysmal neurologic symptoms. This review outlines the indications for long-term video-electroencephalography (VEEG) for typical elective admissions to a specialized inpatient setting. The common techniques used in EMUs to obtain diagnostic information are reviewed. The added benefit of safety measures and clinical testing above that available for routine or long-term ambulatory electroencephalography is also discussed. The indications for admission to the EMU include differential diagnosis of paroxysmal spells, characterization of seizure types, presurgical epilepsy evaluations, seizure quantification, monitoring medication adjustment in a safe setting, and differentiation between seizures and side effects. We conclude that the appropriate use of this specialized testing can lead to an early and correct diagnosis in a variety of clinical circumstances. The EMU evaluation is considered the gold standard test for the definitive diagnosis of epilepsy and seizure-like spells. K E Y W O R D Sepilepsy monitoring, epilepsy surgery, inpatient specialized testing, nonepileptic events of Virginia

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Section: Anticipated Course Of Treatment In Emu For Medical and Presumentioning

confidence: 99%

Indications and methodology for video‐electroencephalographic studies in the epilepsy monitoring unit

et al. 2017

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“…There is a close relation between supersensitivity phenomena and the "withdrawal syndrome" observed after withdrawal from long-term administration of CNS-depressant drugs such as morphine, ethanol, barbiturates and neuroleptics ( Sharpless 1964, 1969, Collier 1966, 1968, Bernardi & Palermo Net0 1979, Bernardi et al 1980. In rats, the main characteristics of this syndrome are the loss of weight, some comportamental and neurologic signs indicative of tolerance and an hyperexcitability state char-acterized by a greater tendency to convulsions, independent of the pattern and nature of the elicitor stimuli ( Essig 1967, Kafant et af. 1971.…”

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confidence: 99%