2006
DOI: 10.1590/s0004-28032006000100012
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Clinical and biochemical features of autoimmune hepatitis in 36 pediatric patients

Abstract: -Background -Few studies on autoimmune hepatitis have enrolled non-Caucasian groups. Aims -To evaluate Brazilian children with type 1 and 2 autoimmune hepatitis regarding outcome and clinical and biochemical parameters.Patients and Methods -Thirty-six patients were submitted to a protocol that evaluated the clinical history, physical and biochemical data, and the course of the disease. Twenty-four children had type 1 autoimmune hepatitis, seven had type 2 and five had unclassified autoimmune hepatitis. Most pa… Show more

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Cited by 24 publications
(20 citation statements)
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“…However, Porta (17) did not find weight or height differences in children with AIH and Bellomo-Brandão et al (1) did not observe low stature in patients with type 1 and type 2 AIH. The present study agrees with the two last cited researches, since only two patients presented an H/A z-score below -2, being then classified as bearers of chronic malnutrition with growth delay.…”
Section: Discussionmentioning
confidence: 93%
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“…However, Porta (17) did not find weight or height differences in children with AIH and Bellomo-Brandão et al (1) did not observe low stature in patients with type 1 and type 2 AIH. The present study agrees with the two last cited researches, since only two patients presented an H/A z-score below -2, being then classified as bearers of chronic malnutrition with growth delay.…”
Section: Discussionmentioning
confidence: 93%
“…In the pediatric age group, patients are going through a phase of weight gain, growth and bone formation. However, there are few researches about these parameters in such patients without a study about the specific nutritional deficiencies, such as oligoelements like zinc (Zn) (1,4) . Zn is an essential mineral that is active in several body functions, once it acts as a cofactor for more than 300 enzymes and proteins.…”
Section: Introductionmentioning
confidence: 99%
“…80% of autoimmune hepatitis is type 1, 4% is type 2 and 3% is type 3 which is a rare type (2,3,5,8). The type in which autoantibodies can not be identified, but clinical and histological examination are compatible with AIH is called undefined AIH (11). Autoimmune hepatitis is observed more frequently in girls compared to boys (57-93%) and occurs most commonly at the ages of 10-20 years (mean 10 years of age) (11,(17)(18)(19).…”
Section: Discussionmentioning
confidence: 99%
“…The type in which autoantibodies can not be identified, but clinical and histological examination are compatible with AIH is called undefined AIH (11). Autoimmune hepatitis is observed more frequently in girls compared to boys (57-93%) and occurs most commonly at the ages of 10-20 years (mean 10 years of age) (11,(17)(18)(19). We found female subjects with a rate of 64.5% and the mean age to be 12 years.…”
Section: Discussionmentioning
confidence: 99%
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