Clinical &amp; angiographic profile of young patients (&lt;40 years) with acute coronary syndrome

Wadkar, Abhishek; Sathe, Anuj; Bohara, Deepak; Shah, Hetan; Mahajan, Ajay; Nathani, Pratap

doi:10.1016/j.jicc.2014.02.009

Cited by 5 publications

(11 citation statements)

References 19 publications

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“…STEMI was the most common clinical manifestation in this study and studies conducted by Tamrakar et al, 27 Wadkar et al, 28 and Sharma et al, 29 whereas NSTEMI and UA were more common in Hoo et al, 30 Iragavarapu et al 31 The most frequent angiographic procedure in this study is SVD, which is comparable to studies by Pathak et al, 32 Suresh et al, 33 and Al‐Koubaisy et al 34 The LAD contributed 21% of the total volume of the vessels implicated in younger age groups in Badran et al 35 and Ahmed Hussein et al, 36 studies, which are similar to this study. However, Kennelly et al 37 reported that the RCA was the most often affected artery.…”

Section: Discussionsupporting

confidence: 68%

“…However, persons under the age of 40 have 5%–10% of MIs. 6 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 The personal and societal costs of early coronary disease are significant, despite the fact that MIs in younger patients are typically associated with a good prognosis. 11 , 17 , 33 Young people who have ACS experience early morbidity and mortality during what should be their most productive years of life.…”

Section: Discussionmentioning

confidence: 99%

“…The majority of ACS affects people over the age of 40. However, persons under the age of 40 have 5%–10% of MIs 6,19–22 . The personal and societal costs of early coronary disease are significant, despite the fact that MIs in younger patients are typically associated with a good prognosis 11,23,24 .…”

Section: Discussionmentioning

confidence: 99%

“…However, persons under the age of 40 have 5%-10% of MIs. 6,[19][20][21][22] The personal and societal costs of early coronary disease are significant, despite the fact that MIs in younger patients are typically associated with a good prognosis. 11,23,24 Other anti-anginals 30 15 Abbreviations: ACE, angiotensin-converting enzyme; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention.…”

Section: Discussionmentioning

confidence: 99%

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Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross‐sectional retrospective study

Murugan

Balasubramaniyan²,

Mathiyalagan

et al. 2023

Health Science Reports

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Background and Aims The prevalence of acute coronary syndrome (ACS) has been rising in the younger population worldwide. To fully comprehend the effects of the condition, it is crucial to examine the evolving characteristics and treatment options. The purpose of this study is to evaluate the characteristics and treatment analysis for young ACS patients in a tertiary care setting. Methods This cross‐sectional, retrospective, single‐center study included a random sample of patients who had been hospitalized for ACS over the period of a year. We collected and analyzed data on risk factors, diagnoses, angiographic patterns, and potential treatments. Results The study involved 198 young ACS patients in total. The majority of patients (57%) had no risk factors, and the majority of them (44%) had ST‐elevation myocardial infarction (STEMI) as their diagnosis. The most common type (48%) was single‐vessel disease (SVD). Statins and antiplatelet medications made up the majority of the patients’ nonsurgical treatments (88% and 87%, respectively). A statistically significant difference exists between young and older ACS patients with gender ( p < 0.01). However, it is not clinically relevant. Conclusion Men were the majority of young ACS patients, and STEMI, SVD were more prevalent. The majority of young ACS patients had no significant risk factors. To determine the risk factors of young ACS patients, a more thorough case–control study is critically needed.

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Section: Discussionsupporting

confidence: 68%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross‐sectional retrospective study

Murugan

Balasubramaniyan²,

Mathiyalagan

et al. 2023

Health Science Reports

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“…In Aggarwal A et al 2014, we found that a recent increase in the prevalence of hypertension [8.86% (2001-2002) to 27.7% (2009-2010)] and dysglycemia [7.6% (2001-2002) to 36.15% (2009-2010)] in young CAD [14]. In spite of that in Wadkar et al, 2014 systemic hypertension and diabetes mellitus are well established risk factors for atherosclerosis, they may not be prevalent in younger age groups as in older ones, the results were observed with only 14.5% were diabetic and 19% were hypertensive in young patients [15]. In our study hyper tension and diabetes mellitus were significantly higher in group B with age (≥45years) than group A (<45 years).…”

Section: Discussionmentioning

confidence: 89%

Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients

Ebeid¹,

Farid²,

Ahmed³

et al. 2020

CCR

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Objectives: this study aimed to study the pattern of risk factors & angiographic features of CAD in young patient aged < 45 in comparison with older patients in a sample of Egyptian patients. Background: Egypt is one of the developing countries where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity of young adults (aged < 45 years) with coronary artery disease (CAD). Methods: Our study was a prospective, cross sectional study conducted at multicenter hospitals included 300 patients with coronary artery disease ( CAD), group I comprised of one hundred patients aged < 45 years old and group II comprised of two hundred patients ≥ 45 years old who underwent coronary angiography at National Heart Institute, Menoufia university hospital from October 2018 to April 2019. Results: Smoking and positive family history were significantly higher in group I with age (<45 years) than group II (≥45years). HTN, DM, obesity were significantly higher in group II with age (≥45years) than group I (<45 years). The most common clinical presentation was STEMI were significantly higher in group I than group II & SCAD was in the second order with significantly higher in group II than in group I. One vessel and two vessel disease were most prominent in group I versus group II while MVD was most prominent in group II versus group I with significant P value 0.010. Type A and B lesions were the most common types of lesion in group I, while type C lesion was more common in group II than group I, with significant P value (0.019). Calcified, bifurcational and ostial lesions were most prominent in group II with highly significant P value (<0.001) in calcified lesions. Conclusion: Primordial prevention about smoking cessation and life style modification in cutting down obesity will be important epidemiological tool. Awareness on this topic, importance of golden hour and early diagnosis and treatment will have huge economic impact as sizeable number of patients present late.

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Risk factors, lab parameters, angiographic characteristics and outcomes of coronary artery disease in young South Asian patients: a systematic review

Agrawal,

Lamichhane,

Eghbali

et al. 2023

J Int Med Res

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This systematic review provides a qualitative summary of the risk factors, angiographic characteristics, treatment, and complications of young South Asians with coronary artery disease (CAD). PubMed, Embase, and Google Scholar were searched to identify research articles published between 1 January 2010 and 13 November 2022. Studies in patients aged 18 to 45 years that were conducted in South Asian countries, were published in the English language, and included information on patients’ clinical profiles and at least two risk factors for young CAD were included in the review. Smoking, dyslipidemia, high body mass index, increased high-sensitivity C-reactive protein, and hyperhomocysteinemia were observed in high proportions in young patients with CAD. Single-vessel disease was more common than multi-vessel disease in young CAD. The complications of CAD such as arrhythmias, cardiogenic shock, and heart failure were also commonly observed in young patients. Large-scale health promotion activities that curb modifiable risk factors such as smoking, obesity, and a sedentary lifestyle should be conducted in South Asian countries.

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Clinical & angiographic profile of young patients (<40 years) with acute coronary syndrome

Cited by 5 publications

References 19 publications

Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross‐sectional retrospective study

Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross‐sectional retrospective study

Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients

Risk factors, lab parameters, angiographic characteristics and outcomes of coronary artery disease in young South Asian patients: a systematic review

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