Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross‐sectional retrospective study

Murugan, Jagannaathan; Balasubramaniyan, Jayanty Venkata; Mathiyalagan, Praveen Kumar; Ramesh, Yashwanth; Selvam, Meera; Charley, Chris; Muralidharan, Harini; Venati, Rishitha; Dhanasekaran, Indrani Devi; Ganesan, R

doi:10.1002/hsr2.1141

Cited by 2 publications

(2 citation statements)

References 32 publications

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“… 23 . PCI was the treatment of choice for young patients with ACS in accordance with previous studies 24 . Our study affirms this with 82% of young patients managed with PCI.…”

Section: Discussionmentioning

confidence: 64%

Acute coronary syndrome in young (≤45 years) patients: a multi-centre observational study

Shrateh,

Al-Tawil,

Awad

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction: Acute Coronary Syndrome (ACS) in young individuals (≤45 y) is increasingly recognized as a significant health concern, yet research in this demographic remains limited, particularly within the Palestinian context. This study aims to bridge this gap by comprehensively investigating the clinical characteristics, age-specific profiles, gender disparities, treatment modalities, and angiographic patterns of ACS in young patients compared to their older counterparts. Materials and Methods: A multicenter observational study was conducted, enrolling 468 participants aged 18-55 diagnosed with ACS and admitted to three prominent Palestinian hospitals. Data were collected from medical records, and statistical analysis was performed to assess demographic characteristics, clinical presentations, risk factors, treatment strategies, and outcomes. Results: The majority of participants were male (87%), with a higher proportion in the older age group (>45 y). Clinical presentations varied, with Non-ST Segment Elevation Myocardial Infarction (NSTEMI) being the most common diagnosis (48%). Risk factors such as smoking, hypertension, and diabetes were prevalent, with notable gender and age-specific differences. Percutaneous Coronary Intervention (PCI) was the predominant treatment strategy (83%), with consistent medication use across age groups. Conclusion: ACS in young patients poses a significant public health challenge in Palestine, necessitating tailored preventive strategies and comprehensive management approaches. Understanding the unique demographic and clinical characteristics of young ACS patients is crucial for informing targeted interventions and policies aimed at reducing the burden of cardiovascular disease in this population. These findings contribute valuable insights to the existing literature and underscore the importance of further research in this area to improve outcomes and mitigate the impact of ACS in young individuals globally.

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“… 23 . PCI was the treatment of choice for young patients with ACS in accordance with previous studies 24 . Our study affirms this with 82% of young patients managed with PCI.…”

Section: Discussionmentioning

confidence: 64%

Acute coronary syndrome in young (≤45 years) patients: a multi-centre observational study

Shrateh,

Al-Tawil,

Awad

et al. 2024

Annals of Medicine &Amp; Surgery

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“…CAD, once primarily associated with older individuals with established risk factors, has seen a dramatic shift in its demographic profile (1). The emergence of CAD in younger patients, especially those with acute coronary syndrome (ACS), presents unique challenges and requires a thorough understanding of its patterns and underlying factors (2). Historically, CAD in the young was often linked to congenital anomalies or rare genetic disorders.…”

Section: Introductionmentioning

confidence: 99%

Pattern of Coronary Artery Disease in Young Patients with Acute Coronary Syndrome

Rehman,

Ahmed,

Alam

et al. 2023

JHRR

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Background: Coronary artery disease (CAD), historically considered a malady of the elderly, has increasingly emerged as a significant health concern among young adults, including individuals in their third or fourth decade of life. Objective: The primary aim of the study is to identify the pattern of coronary artery disease in young patients with acute coronary syndrome (ACS). Methods: This retrospective observational study was conducted at a tertiary cardiac care center in Rawalpindi from July 2023 to November 2023. The study included a cohort of 180 young patients aged less than 45 years who were diagnosed with ACS. These patients were identified from medical records and databases over a defined time period. Detailed demographic data, including age, gender, and pertinent medical history, were extracted from the medical records of each patient. This information facilitated a comprehensive understanding of the patient population under investigation. Results: Data were collected from 180 patients. The analysis of clinical profiles and demographics revealed a diverse patient population. The study cohort comprised individuals with a mean age of 39 years. Male patients predominated, constituting approximately 65% of the cohort. Among the study participants, 40% had a documented history of smoking, while 20% reported a family history of CAD. Hypertension was the most prevalent risk factor, affecting nearly 50% of the patients, followed by hyperlipidemia (30%) and diabetes (20%). Conclusion: It is concluded that coronary artery disease (CAD) is not confined to older age groups but can significantly impact young individuals aged less than 45 years presenting with acute coronary syndrome (ACS). The prevalence of traditional risk factors and genetic predisposition among these patients underscores the multifactorial nature of CAD in this demographic.

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Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross‐sectional retrospective study

Cited by 2 publications

References 32 publications

Acute coronary syndrome in young (≤45 years) patients: a multi-centre observational study

Acute coronary syndrome in young (≤45 years) patients: a multi-centre observational study

Pattern of Coronary Artery Disease in Young Patients with Acute Coronary Syndrome

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