Clerodendrum colebrookianum, a Folk Remedy for the Treatment of Hypertension in Northeastern India

Extract from Clerodendron colebrookianum Walp protects rat heart against oxidative stress induced by ischemic–reperfusion injury (IRI)

“…Arial part of the CC was collected from Guwahati (Assam, India) during April to August, identified and authenticated in the Department of Botany, Gauhati University, Assam, using some references (Nath and Bordoloi, 1991).…”

“…The Mizo people of northeast India claim that the low incidence of hypertension among their community members is due to the regular use of the tender leaves and shoot of CC in their diet (Nath and Bordoloi, 1991). The roots of the same plant have been reported to have anthelminthic (Banerjee, 1936) and antibacterial (Hosozowa et al, 1974) properties and are used to treat bronchitis, asthma, fever, stomach troubles, syphilis and gonorrhoea (Singh et al, 1995) in tribal populations.…”

“…Clerodendron colebrookianum (CC) Walp (Family-Verbenaceae) is a perennial shrub indigenous to the northeastern region of India as well as in many Southeast Asian countries and grows up to an altitude of 1700 m (Nath and Bordoloi, 1991;Goswami et al, 1996;Wang et al, 2000). The Mizo people of northeast India claim that the low incidence of hypertension among their community members is due to the regular use of the tender leaves and shoot of CC in their diet (Nath and Bordoloi, 1991).…”

Evaluation of mechanism for antihypertensive action of Clerodendrum colebrookianum Walp., used by folklore healers in north-east India

“…Clerodendrum colebrookianum Walp., (Family-Verbenaceae) commonly known as East Indian Glory Bower (English), Kuthap (Manipuri), Phuihong (Naga), Phuinum (Mizo), Shada bhait (Bangla), Nephaphu (Assamese) is a popular folk medicines of north-east India for the treatment of hypertension (Deb and Dutta, 2012;Deb et al, 2011;Devi et al, 2003Devi et al, , 2011Temjenmongla, 2005;Devi and Sharma, 2004;Nath, and Bordoloi, 1991;Mao et al, 1995;Das et al, 2008). Apart from antihypertensive property, the plant has been reported to be used by traditional practitioners as anticolics pain for infants, anti-diabetic in Mizoram state (Sharma et al, 2001), for treatment helminthic infection, dizziness and greenish swelling (gland) in Nagaland state (Jamir et al, 1999), for stomach disorder, headache in Arunachal Pradesh state (Namsa et al, 2011) and for treatment of skin disease, cough, and dysentery in Manipur state of north-east India (Singh and Singh, 2009).…”

In-vitro and in-vivo antioxidant activity of different extracts of the leaves of Clerodendron colebrookianum Walp in the rat

“…Clerodendron colebrookianum Walp (Family Verbenaceae) is distributed widely in South and South-East Asia (Wang et al 2000). In India, it mainly grows in the northeastern region up to an altitude of 1700 m (Nath & Bordoloi 1991;Goswami et al 1996). In Indian traditional medicine, the leaves of C. colebrookianum (locally known as``Nefafu'') are mostly used in the treatment of hypertension (Nath & Bordoloi 1991, 1988.…”