Cleft–Orthognathic Surgery

Posnick, Jeffrey C.

doi:10.1016/b978-1-4557-2698-1.00032-0

Cited by 11 publications

(8 citation statements)

References 144 publications

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“…New bone is deposited at the alveolar process to support teeth development and eruption. 6164 Preserving the condylar growth center, as in our case, could, however, minimize the potential of asymmetry or deformity.…”

Section: Discussionmentioning

confidence: 80%

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

Chatzistefanou

Kabesi

Paraskevopoulos

et al. 2016

International Journal of Clinical Pediatric Dentistry

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Ewing’s sarcoma (ES) is an uncommon aggressive bone malignancy that mainly affects children and adolescents. Mandible involvement is quite rare and usually represents metastasis from another skeletal site. Combined therapy including wide surgical resection and preoperative and postoperative chemotherapy has been demonstrated as the mainstay of therapeutic approach. As improved therapeutic modalities have significantly increased survival over the last decades, functional and esthetic reconstruction of the postmandibulectomy defect is usually necessary for patient’s total rehabilitation. We report a case of ES of the mandible with special consideration to the postresection spontaneous structural and functional regeneration of the mandible.How to cite this articleChatzistefanou I, Kabesi S, Paraskevopoulos K, Koliouskas D, Antoniades K. Ewing’s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration. Int J Clin Pediatr Dent 2016;9(3):273-277.

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Section: Discussionmentioning

confidence: 80%

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

Chatzistefanou

Kabesi

Paraskevopoulos

et al. 2016

International Journal of Clinical Pediatric Dentistry

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“…A mechanical blender could resolve this issue. According to orthognathic surgeons, hard food chewing occurs mainly on 1st molar and 2nd premolar areas [2]. Molars are perfect for grinding and crushing, and premolars are suitable for tearing and biting.…”

Section: Discussionmentioning

confidence: 99%

Mechanical Digestion of Broccoli through Chewing and its Impact on Myrosinase Activity

2023

ANFS

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Myrosinase activity on broccoli glucosinolates has been widely and extensively discussed. Purpose: Studies on cruciferous vegetables, especially broccoli, have gained significance in the fight against cancer. Glucosinolates in broccoli transformation into sulforaphane occur after its exposure through chewing. However, the relationship between individual chewing patterns and denture morphology has not been studied extensively. Research on human digestion has demonstrated how the mechanical breakdown of larger food particles into smaller ones is a crucial precursor to chemical food breakdown. This study is a comparative analysis of how chewing on broccoli tissues by different individuals enables the enzyme myrosinase to break down broccoli glucosinolates chemically. We investigate the individual chewing patterns linked to the surface anatomy of the pre-molars and molars and the myrosinase activity on broccoli glucosinolates. Methods: Three individuals chewed a 4-millimeter broccoli floret four times sequentially (2 grams), and we measured the floret length at each bite until the sample was ground. Then, we combined the chewed broccoli with distilled water, filtered it, and myrosinase activity was measured using photo spectrometric measurements and an agar diffusion test. Individual pre-molars and molars samples were measured in millimetres. Results: Data from the three human chewing mechanisms compared to the mechanical breakdown performed by an automatic mixer shows different and individually specific values. Conclusion: Individual chewing patterns link to the unique surface anatomy of the pre-molars and molars, subsequently impacting the myrosinase activity on broccoli glucosinolates’ breakdown individually

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“…All participants underwent LeFort I osteotomy with pterygomaxillary disjunction and down-fracture, as described in the literature. 2–4 For CO, the newly-mobile maxilla was placed into a prefabricated acrylic surgical splint to obtain intermaxillary fixation then wired together. The newly-mobile maxilla was secured into the splint in its baseline position for DO.…”

Section: Methodsmentioning

confidence: 99%

“…Conventional osteotomy (CO), or en bloc maxillary advancement in a single stage, is considered a reliable and safe procedure among patients with primary dentofacial deformities. 1–3 The prevalence of maxillary hypoplasia among patients with cleft palate with or without cleft lip (CP ± L) is high, with as many as 65% of patients benefitting from surgical advancement of the maxilla. 4 Individuals with CP ± L, however, present with increased severity of hypoplasia, multi-dimensional maxillary deficiency, and scar tissue from prior surgery, making the conventional approach to LeFort I osteotomy more technically complex with relatively greater chance of negative post-operative sequelae in these patients, particularly relapse of the maxillary segment.…”

Section: Introductionmentioning

confidence: 99%

Does Distraction Lower Risk of VPI Compared to Conventional Maxillary Advancement? A Retrospective Cohort Study of Adolescents with Cleft Palate

Kinter

Susarla

Delaney

et al. 2022

The Cleft Palate Craniofacial Journal

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Objective To determine whether method of maxillary advancement in adolescents with cleft palate with or without cleft lip (CP ± L) influences post-operative velopharyngeal function. Design Retrospective cohort. Setting Pediatric Tertiary Care Hospital. Participants One hundred and ninety-nine patients with CP ± L after LeFort I osteotomy for maxillary advancement at our institution between January 2007 and June 2019. Interventions LeFort I osteotomy via distraction osteogenesis (DO) or conventional osteotomy (CO). Main Outcome Measures Patients who underwent DO or CO were compared for the presence of new velopharyngeal insufficiency (VPI), as measured by perceptual rating by a craniofacial speech-language pathologist. Of the 199 patients who underwent maxillary advancement, 126 were available for analysis. The DO group was younger, male, and had more severe maxillary hypoplasia. Following surgery, 17/41 (41.5%) of the DO group had new VPI, compared to just 23/85 (27.1%) of the CO group. After adjusting for cleft type and predicted maxillary advancement, however, there was not sufficient evidence to reject the null hypothesis of no difference in risk of post-operative VPI between the two surgical groups (prevalence ratio [PR] 1.40, 95% CI 0.68-2.90). Increased prevalence of VPI after DO versus CO was primarily observed among patients with a pre-operative velopharyngeal need ratio < 0.8 (PR = 2.01, 95% CI 0.79-5.10) and patients with normal velopharyngeal function pre-operatively (PR = 2.86, 95% CI 0.96-8.50). Our results suggest an increased rather than decreased risk of VPI following DO relative to CO. This association is primarily seen among those with a smaller velopharyngeal ratio or perceptually normal velopharyngeal function pre-operatively.

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Cleft–Orthognathic Surgery

Cited by 11 publications

References 144 publications

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

Mechanical Digestion of Broccoli through Chewing and its Impact on Myrosinase Activity

Does Distraction Lower Risk of VPI Compared to Conventional Maxillary Advancement? A Retrospective Cohort Study of Adolescents with Cleft Palate

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