Clear cell “sugar“ tumor of the lung — case report

Kosjerina, Zdravko; Kuhajda, Ivan; Koledin, Milos; Koledin, Bojan; Stojanović, Miloš; Pocuca, Marta

doi:10.2478/s11536-012-0049-1

Cited by 2 publications

(4 citation statements)

References 16 publications

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“…PEComas are quite vascular with vascular channels traversing through the tumor and cells are bland-looking polygonal or spindle cells with abundant cytoplasm with intracytoplasmic PAS positive fine glycogen granules which are diastase sensitive. 11,12 Stroma with abundant small vascular channels with hyalinization unlike this case are seen in PEComas. 10 Paraganglioma has more striking anisonucleosis without prominent large nucleoli, as seen in ASPS.…”

Section: Discussionmentioning

confidence: 63%

“…[1][2][3][4][5][6][7][8][9][10][11][12][13] Immunohistochemistry for TFE3 is confirmatory of the diagnosis. It accounts for 0.5%-1% of all tissue sarcomas and is most commonly found in children and young adults.…”

Section: Introductionmentioning

confidence: 99%

“…Characteristic histopathological examination shows tumor cells in alveolar or nesting pattern, with mildly pleomorphic round to polygonal large nuclei with prominent nucleoli and cytoplasmic PAS positive diastase resistant needle-shaped crystals and granules. [1][2][3][4][5][6][7][8][9][10][11][12][13] Immunohistochemistry for TFE3 is confirmatory of the diagnosis. [1][2][3] There are very limited cytology case reports with definite diagnosis of Alveolar soft part sarcoma (ASPS).…”

Section: Introductionmentioning

confidence: 99%

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Alveolar soft part sarcoma: A case report with emphasis on some unusual cytological features

Sood

Gulia

2017

Diagnostic Cytopathology

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Alveolar soft part sarcoma is a very rare, slow growing highly angiogenic tumor with poor prognosis. Most common site in children and infants is head and neck region and in adults it most commonly occurs in extremities especially thigh. In our case study, an 8 years old female patient presented with a gradually progressive left shoulder lump. FNAC from the lesion showed cellular smears with polyhedral and spindly cells showing abundant finely vacuolated cytoplasm, nuclear pleomorphism, intranuclear pseudoinclusions, and few bare nuclei. Perivascular arrangement of cells was peculiar in addition to the presence of intracytoplasmic metachromatic PAS positive diastase resistant granules. A presumptive diagnosis of alveolar soft part sarcoma with differentials of granular cell tumor and PEComa was considered and the lesion was excised. Although the histopathological features were not characteristic (ie, showing mainly solid pattern without classic alveolar pattern), immunohistochemistry were diagnostic (negative for S 100, Desmin, Cytokeratin, EMA, and moderate to strong nuclear positivity for TFE3). Thus, the diagnosis of alveolar soft part sarcoma was established. This case is being presented for its rarity and unique cytological and histopathological features.

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Section: Discussionmentioning

confidence: 63%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Alveolar soft part sarcoma: A case report with emphasis on some unusual cytological features

Sood

Gulia

2017

Diagnostic Cytopathology

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“…CCTL usually presents as asymptomatic peripheral solitary nodule with no evidence of cavitation or calcification [13]. The typical characteristics of the CCTL on contrastenhanced CT scans are the intense heterogeneous enhancement in the arterial phase and washout in the delay phase [14]. A single report describes an extensive FDG uptake of the benign tumor [5].…”

Section: Discussionmentioning

confidence: 99%

PEComa of the Lung: a Rare Entity

Pischik¹,

Zinchenko²,

Maslak³

et al. 2019

JCR

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Background: Perivascular epithelioid cell tumor (PEComa) is extremely rare neoplasm, especially for the pulmonary localization. Clear-cell tumor of the lung, arising from perivascular epithelioid cells, has mainly asymptomatic and benign course. The diagnosis is confirmed on the immunohistochemical examination. The tumors are usually benign, but there are some sarcoma-like masses. Treatment of choice is a surgical resection. Case Report: We report a case of benign PEComa in a 64-year old non-smoking female, accidentally found on a chest X-Ray. VATS anatomic segmentectomy of basal segments was performed. The immunohistochemical examination showed typical features of PEComa. Conclusion: PEComa should be considered in the differential diagnosis of pulmonary nodules. Surgical resection is a treatment of choice followed by immunostaining.

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Clear cell “sugar“ tumor of the lung — case report

Abstract: Abstract

Cited by 2 publications

References 16 publications

Alveolar soft part sarcoma: A case report with emphasis on some unusual cytological features

Alveolar soft part sarcoma: A case report with emphasis on some unusual cytological features

PEComa of the Lung: a Rare Entity

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