Clear cell odontogenic carcinoma of the mandible

Mosqueda‐Taylor, Adalberto; Meneses‐García, Abelardo; Rivera, Luz María Ruíz‐Godoy; Suárez‐Roa, María de Lourdes

doi:10.1034/j.1600-0714.2002.00133.x

Cited by 26 publications

(13 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mean age at presentation was 52.8 years in our series, and this finding ? [9]. The most common site of occurrence was the mandible: 51 (76.1%) tumors were encountered in the mandible and 16 (23.9%) in the maxilla, with an overall mandible/maxilla ratio of 3.2:1.…”

Section: Discussionmentioning

confidence: 96%

Clear cell odontogenic carcinoma: report of 6 cases and review of the literature

et al. 2010

View full text Add to dashboard Cite

Clear cell odontogenic carcinoma (CCOC) is a rare malignant tumor. To date, only 67 cases were described in the English literature and complete understanding of the behavior of CCOC was based on limited case reports. In this article, we reported 6 additional cases and reviewed the relevant literature. Our cases included 4 men and 2 women with an average age of 52.8 years. The tumors were all in the mandible and presented as poorly marginated radiolucencies. Patients were treated with resection. All cases consisted of islands and sheets of clear cells that were separated by fibrous septa. Immunohistochemically, the tumor cells were positive for pan-cytokeratins, CK14, CK19, and epithelial membrane antigen, but negative for S-100 protein, smooth muscle actin, desmin, human melanoma antigen, CD3, CD45, and glial fibrillary acidic protein. A series of literature review disclosed the tumor has a female preponderance (44 female vs. 23 male, 1.9:1). The mean age was 54.5 years and the predominant site was the mandible (51, 76.1%). Forty-seven (70.1%) patients were initially treated with surgical resection, 15 (22.4%) patients underwent curettage or enucleation, and 1 patient was treated with chemotherapy. Nine patients had a neck dissection in addition to a surgical resection. Seven (9.6%) patients received postoperative radiotherapy. The recurrence rate after resection was lower than conservative therapy (29 vs. 86.7%). Nine patients died of the tumor. CCOC is a potentially aggressive lesion and owing to a high recurrent rate of conservative measure; therefore, radical surgical treatment is recommended and long-term follow-up is necessary.

show abstract

Section: Discussionmentioning

confidence: 96%

Clear cell odontogenic carcinoma: report of 6 cases and review of the literature

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Later on, its local aggressive growth, frequent recurrences, and occasional metastases recorded in several cases led some authors to consider it as an odontogenic carcinoma. [5–9]…”

Section: Discussionmentioning

confidence: 99%

“…[921–2325] The reports on immunohistochemical findings of CCOC have been inconsistent. Immunoreactivity for CKs, specifically for CKs 8, 13, 18 and 19 has been reported.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Clear cell odontogenic carcinoma of maxilla: A case report and mini review

Swain¹,

Dhariwal

Ray

2013

J Oral Maxillofac Pathol

View full text Add to dashboard Cite

Clear cell odontogenic carcinoma is a rare odontogenic tumor occurring predominantly in posterior mandible during 5th-7th decades with a female predilection. It is a potentially aggressive tumor, capable of frequent recurrences and loco-regional and distant metastases. Till date, only 73 cases have been reported in the literature. Current case is of a 55-year-old woman with tumor mass extending from canine to molar region on the left maxillary arch. Being locally aggressive tumor with the capacity to metastasize, it demands to be distinguished from other primary and metastatic clear cell tumors of the oral and maxillofacial region. A brief compilation of the reported cases is being attempted in the current article to better understand the behavior of the tumor.

show abstract

“…Logoregional recurrence has been reported in approximately one-third of patients and the rate of distant metastases is 14 % [47][48][49][50]. Histologically, CCOC has been characterized as either monophasic or biphasic.…”

Section: Hyalinizing Clear Cell Carcinoma Versus Clear Cellmentioning

confidence: 99%