This article analyzes Higher Education students’ development of interpersonal competences when using Information and Communication Technologies. The participating sample was made up of 1490 students from three Spanish universities: Complutense University of Madrid (Spain), Pablo de Olavide University (Spain), and National Distance Education University (UNED). The data were collected through a questionnaire called “Basic digital skills 2.0 of university students” COBADI® (Registered trademark: 2970648). A factorial analysis was performed to determine possible groupings of representative factors and subsequently the trees technique was applied by running the CHAID (Chi-squared Automatic Interaction Detector) algorithm. This made it possible to develop a map of possible differences between universities, ages, and gender of students. The results showed that university students have higher competences in communicating through interactive presentations and video-images, as well as in collaborating and working with documents online through mobile devices.