Citrobacter koseri folliculitis of the face

Raia, Daniele Domenico; Barbareschi, M.; Veraldi, Stefano

doi:10.1007/s15010-015-0734-5

Cited by 7 publications

(5 citation statements)

References 13 publications

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“…Previously reported skin manifestations of C. koseri include cellulitis in immunocompromised patients, as well as skin abscesses and diabetic foot ulcers . Raia et al .…”

Section: Discussionmentioning

confidence: 99%

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Asymptomatic facial nodules

et al. 2018

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“…Previously reported skin manifestations of C. koseri include cellulitis in immunocompromised patients, as well as skin abscesses and diabetic foot ulcers . Raia et al .…”

Section: Discussionmentioning

confidence: 99%

“…Previously reported skin manifestations of C. koseri include cellulitis in immunocompromised patients, as well as skin abscesses and diabetic foot ulcers . Raia et al . reported a case of extensive facial Citrobacter folliculitis in a healthy 15‐year‐old boy with a background history of facial acne.…”

Section: Discussionmentioning

confidence: 99%

Asymptomatic facial nodules

et al. 2018

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“…These changes included elimination of the gram-negative bacilli, in particular Citrobacter koseri and Enterococcus spp. (faecal streptococci), which presence was reported in the patients with secondary infections like ulcer/decubitus [23] as well as individuals with acne [24] and scalp folliculitis [25]. Furthermore, use of cosmetics containing ImmunatuRNA® lead to subsequent reduction of aerobic grampositive rod-shaped bacteria including genus Bacillus, Alcaligenes and Pantoea, being implicated in the wound infections [26,27] and skin lesions in the post-operative patients [28].…”

Section: Discussionmentioning

confidence: 99%

Skin Beautification with an ImmunatuRNA® Complex: A Natural Complex Based on Yeast RNA and Marine Derivatives on the Human Skin Immunity and Microbiome Composition

Neymann¹

2023

J Immuno Allerg

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The skin is the largest organ of human body implicated in vital physiological and immunological processes, including protection against injury, infections, and environmental exposures. Nevertheless, a number of negative external and internal factors, including increased pollution along with modern lifestyle can significantly influence on the skin immunity, promote aging and reduce regenerative capabilities. Cosmetic formulations based on natural ingredients, including plant and marine/algae extracts, and microbial-derived bio-actives may help to maintain healthy skin condition and protect its beautiful appearance. The ImmunatuRNA®* (*The trademark ImmunatuRNA® is a registered trademark in the European Union EUTM 018365297 and Great Britain UK00003630172. Any reference to the registration of the ImmunatuRNA® trademark applies to the designated territories), a signature complex (VRFD SA/VERDILAB Switzerland) based on the Natural RNA molecules obtained from yeasts, with added marine exopolysaccharides and natural hyaluronic acid with potential benefits for antibacterial and antiradical defense and maintaining skin detox homeostasis. Therefore, the main aim of this study is to experimentally assess the ImmunatuRNA® complex capabilities to enhance natural skin antioxidant defenses and protection against oxidative stress, by using human fibroblast cell culture. Additionally, this study will investigate the effects of the skincare products with added ImmunatuRNA® complex on the skin microbiome composition in the group of healthy adults with various skin types. The results obtained from the in vitro studies consistently demonstrated that treatment with an ImmunatuRNA® complex protects human fibroblasts against exposure to pro-oxidants, while at the same time enhances anti-oxidative defenses of these cells, demonstrated as reduced formation of free radicals and upregulation of SIRT-1 protein. Furthermore, the cosmetic intervention carried on the group of 10 healthy human volunteers with different skin types (oily, dry, combined, normal) aged between 23 and 65 years old demonstrated that using interchangeably of two cosmetic products-a Natural Moisturizer Probiotic Cream and Natural Detox Replenishing Face Mask containing the ImmunatuRNA® complex, for 4-weeks led to favorable changes in the composition of skin microbiome observed as a reduction of relative abundance of adverse microorganisms, previously linked to the skin inflammation and infections, such as Citrobacter koseri, Bacillus spp., Enterococcus spp., Alcaligenes spp., Pantoea spp. and Staphylococcus aureus. Based on following results, the use of skincare products containing the ImmunatuRNA® complex can help maintain a healthy skin microbiome while possibly preventing against infections and negative environmental exposures, in particularly against oxidative stress in healthy adults with all types of skin with age range 23-65 years old.

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“…C. koser i is an uncommon Gram‐negative aerobic intestinal bacillus that does not usually reside in skin . It is known to infect chronic ulcers, and in this case may have secondarily infected the finger.…”

Section: Discussionmentioning

confidence: 99%