Cirrhotic cardiomyopathy: is there any correlation between the stage of cardiac impairment and the severity of liver disease?

Hammami, R.; Boudabbous, Mouna; Jdidi, J.; Trabelsi, Fatma; Mroua, Fakher; Kallel, R.; Amouri, A.; Abid, Dorra; Tahri, N.; Abid, Leïla; Kammoun, S.

doi:10.1080/19932820.2017.1283162

Cited by 24 publications

(53 citation statements)

References 32 publications

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“…In most studies controls had no cardiac dysfunction but in two studies[35,25] 4.7% (overall 15 out of 318) controls were diagnosed with LVDD.…”

Section: Resultsmentioning

confidence: 99%

“…In our systemic analysis the data about LVDD prevalence in cirrhotic patients depending on Child-Pugh classes was available from 5 studies (365 patients overall)[16,24,25,32,34] and only Bhuin et al[16] found LVDD being associated with severity of liver cirrhosis ( P < 0.005). Other four studies did not find any difference in the severity of LVDD among Child classes[24,25,32,34].…”

Section: Resultsmentioning

confidence: 99%

“…Only three studies reported how many patients with different LVDD grades were in different Child-Pugh classes[16,21,25]. Figure 2 shows that the proportion of patients with higher LVDD grades increases in the presence of more severe cirrhosis.…”

Section: Resultsmentioning

confidence: 99%

“…In Merli et al[37] study patients were divided in two groups: Child-Pugh A-B classes and Child-Pugh C class patients. In order not to lose the data reported in this study we also divided all patients from other 5 studies into the same two groups and analysed all patient data from 6 studies[16,24,25,32,34,37]. LVDD was found in 49.3% (149) of patients of Child - Pugh A+B classes and in 59.7% (86) of Child - Pugh C class patients ( P = 0.051).…”

Section: Resultsmentioning

confidence: 99%

“…Ratio of left ventricle diastolic dysfunction grades in two groups of cirrhotic patients[16,21,25,37] ( P = 0.044, Pearson's Chi-squared test).…”

Section: Resultsmentioning

confidence: 99%

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Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

Stundiene¹,

Sarnelyte²,

Norkutė³

et al. 2019

WJG

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BACKGROUND Liver cirrhosis is a chronic hepatic disease which is associated with cardiovascular abnormalities. Hyperdynamic circulation in liver cirrhosis causes functional and structural cardiac alterations. The prevalence of left ventricle diastolic dysfunction (LVDD) in cirrhotic patients ranges from 25.7% to as high as 81.4% as reported in different studies. In several studies the severity of diastolic dysfunction (DD) correlated with a degree of liver failure and the rate of dysfunction was higher in patients with decompensated cirrhosis compared with compensated. Future directions of comprehensive assessment of cardiac function in cirrhotic patients might provide a better prognosis for these patients. AIM To clarify the correlation between the severity of liver cirrhosis and left ventricle diastolic dysfunction in the existing literature. METHODS Through January and February of 2019 at Vilnius University we conducted a systematic review of the global existing literature on the prevalence of left ventricle diastolic dysfunction in patients with liver cirrhosis. We searched for articles in PubMed, Medline and Web of science databases. Articles were selected by using adequate inclusion and exclusion criteria. Our interest was the outcome of likely correlation between the severity of cirrhosis [evaluated by Child-Pugh classes, Model For End-Stage Liver Disease (MELD) scores] and left ventricle diastolic dysfunction [classified according to American Society of Echocardiography (ASE) guidelines (2009, 2016)], as well as relative risk of dysfunction in cirrhotic patients. Subgroup analyses were performed to evaluate the ratio and grades of left ventricle diastolic dysfunction with respect to cirrhosis severity. RESULTS A total of 1149 articles and abstracts met the initial search criteria. Sixteen articles which met the predefined eligibility criteria were included in the final analysis. Overall, 1067 patients (out of them 723 men) with liver cirrhosis were evaluated for left ventricle diastolic dysfunction. In our systemic analysis we have found that 51.2% of cirrhotic patients had left ventricle diastolic dysfunction diagnosed and the grade 1 was the most prevalent (59.2%, P < 0.001) among them, the grade 3 had been rarely diagnosed - only 5.1%. The data about the prevalence of diastolic dysfunction in cirrhotic patients depending on Child-Pugh Classes was available from 5 studies (365 patients overall) and only in 1 research diastolic dysfunction was found being associated with severity of liver cirrhosis ( P < 0.005). We established that diastolic dysfunction was diagnosed in 44.6% of Child-Pugh A class patients, in 62% of Child B class and in 63.3% of Child C patients ( P = 0.028). The proportion of patients with higher diastolic dysfunction grades increases in more severe cirrhosis presentation ( P ...

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“…In most studies controls had no cardiac dysfunction but in two studies[35,25] 4.7% (overall 15 out of 318) controls were diagnosed with LVDD.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Ratio of left ventricle diastolic dysfunction grades in two groups of cirrhotic patients[16,21,25,37] ( P = 0.044, Pearson's Chi-squared test).…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

Stundiene¹,

Sarnelyte²,

Norkutė³

et al. 2019

WJG

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Cirrhotic cardiomyopathy

Hamoudi

Lee²

2023

Cardio-Hepatology

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Perioperative clinical utility of myocardial deformation imaging: a narrative review

Abuelkasem

Wang

Omer

et al. 2019

British Journal of Anaesthesia

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Preoperative cardiac function is an important predictor of postoperative outcomes. Patients with heart failure are at higher risk of perioperative morbidity and mortality. Left ventricular ejection fraction (LVEF), derived by standard echocardiography, is most frequently used to assess cardiac function in the intraoperative and postoperative periods. Myocardial strain analysis, a measurement of myocardial deformation, can provide additional information to LVEF estimation. Here, we provide an overview of myocardial strain and different methods used to evaluate strain, including speckle tracking echocardiography. Speckle tracking echocardiography is an imaging modality that can analyse and track small segments of the myocardium, which provides greater detail for assessing global and regional cardiac motion and function. We further review the literature to illustrate the value of speckle tracking echocardiography-derived myocardial strain in describing cardiac function and its association with adverse surgical outcomes in the perioperative period, including low cardiac output states, need for inotropic support, postoperative arrhythmias, subclinical myocardial ischaemia, and length of hospital stay.

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Cirrhotic cardiomyopathy: is there any correlation between the stage of cardiac impairment and the severity of liver disease?

Cited by 24 publications

References 32 publications

Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

Cirrhotic cardiomyopathy

Perioperative clinical utility of myocardial deformation imaging: a narrative review

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